Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12463651 | 0.64 | PPARG (0.35) | GBA1 | |
| SCHEMBL9548301 | 0.59 | GBA1 (0.47) | GBA1 | |
| SCHEMBL18644062 | 0.59 | CYP1A2 (0.33) | — | |
| SCHEMBL3877380 | 0.59 | PDCD4 (0.38) | GBA1 | |
| SCHEMBL11790150 | 0.58 | GBA1 (0.50) | GBA1 | |
| SCHEMBL15326632 | 0.58 | GBA1 (0.41) | GBA1 | |
| SCHEMBL6518428 | 0.57 | GBA1 (0.43) | GBA1 | |
| SCHEMBL9500810 | 0.57 | ADRB2 (0.39) | GBA1 | |
| SCHEMBL16254136 | 0.57 | GBA1 (0.43) | GBA1 | |
| SCHEMBL13950209 | 0.55 | GBA1 (0.42) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7518003-B2 | Production process of tetrahydropyran compound and tetrahydropyran compound produced by the production process | SHOWA DENKO K.K. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20080139828-A1 | Reacting 3,4-dihydro-2-alkoxy-2H-pyran with hydrogen in the presence of a catalyst under acidic condition; Grignard reaction solvent or polymer solvent | SHOWA DENKO K.K. (JP) | 2008-06-12 | — | — | US | disclosed |
| CN-101068800-A | Method for producing tetrahydropyran compound and tetrahydropyran compound produced by the production method | SHOWA DENKO KK (JP) | 2007-11-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139828-A1 | Reacting 3,4-dihydro-2-alkoxy-2H-pyran with hydrogen in the presence of a catalyst under acidic condition; Grignard reaction solvent or polymer solvent | HPD, ACR, GRHPR | GBA1 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.