SCHEMBL4496903

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4376098	0.85	ALDH1A1 (0.57)	CMA1KMT2AMAPTLMNAPOLB
	SCHEMBL4392970	0.81	LMNA (0.60)	KMT2AMAPTLMNAPOLBTSHR
	SCHEMBL4378973	0.81	KDM4E (0.55)	MAPTLMNAPOLBALDH1A1IDH1
	SCHEMBL4510969	0.78	CMA1 (0.51)	MIFCD74CMA1KMT2AMAPT
	SCHEMBL4513012	0.78	CMA1 (0.51)	MIFCD74CMA1KMT2AMAPT
	SCHEMBL19048416	0.78	ALDH1A1 (0.62)	MIFCD74CMA1KMT2AMAPT
	SCHEMBL4516793	0.77	POLB (0.48)	KMT2AMAPTLMNAPOLBTSHR
	SCHEMBL4384316	0.77	LMNA (0.50)	KMT2ALMNAPOLBALDH1A1MEN1
	SCHEMBL461145	0.77	MAPT (0.59)	MIFCD74CMA1KMT2AMAPT
	SCHEMBL4512432	0.76	POLB (0.47)	KMT2AMAPTLMNAPOLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.