Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12050193 | 0.73 | GAA (0.45) | DPYDGAAATAD2LMNAMAPT | |
| SCHEMBL1558078 | 0.72 | DPYD (0.59) | DPYDGAAATAD2LMNAMAPT | |
| SCHEMBL7601482 | 0.71 | DPYD (0.49) | DPYDGAAATAD2LMNAMAPT | |
| SCHEMBL8916051 | 0.71 | DPYD (0.49) | DPYDGAAATAD2LMNAMAPT | |
| SCHEMBL1052480 | 0.68 | DPYD (0.53) | DPYDGAAATAD2LMNAMAPT | |
| SCHEMBL190958 | 0.66 | GAA (0.50) | DPYDGAAATAD2LMNAMAPT | |
| SCHEMBL7599067 | 0.66 | DPYD (0.42) | DPYDGAAATAD2LMNAMAPT | |
| SCHEMBL124965 | 0.66 | KMT2A (0.60) | GAALMNAMAPTALDH1A1TSHR | |
| SCHEMBL48228 | 0.66 | DPYD (0.65) | DPYDGAAATAD2LMNAMAPT | |
| SCHEMBL10696940 | 0.66 | DPYD (0.65) | DPYDGAAATAD2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124919-A2 | METHODS FOR MODULATING BONE FORMATION AND MINERALIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-12-02 | — | — | EP | claimed |
| US-20080318987-A1 | METHODS FOR MODULATING BONE FORMATION AND MINERALIZATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-25 | — | — | US | claimed |
| WO-2008103314-A2 | METHODS FOR MODULATING BONE FORMATION AND MINERALIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-08-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318987-A1 | METHODS FOR MODULATING BONE FORMATION AND MINERALIZATION | BMP4, BMP2, SOST | DPYD 3965/4885GAA 2152/4885ATAD2 2963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.