Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48228 | 1.00 | DPYD (0.65) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL1916591 | 0.79 | DPYD (0.63) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL1228163 | 0.79 | DPYD (0.63) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL170251 | 0.79 | DPYD (1.00) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL23622048 | 0.77 | DPYD (0.45) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL21345242 | 0.77 | KDM3B (0.47) | DPYDMAPTGAAALDH1A1CYP2A6 | |
| SCHEMBL6374591 | 0.76 | DPYD (0.59) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL6374582 | 0.76 | DPYD (0.59) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL15798473 | 0.76 | DPYD (0.62) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL65892 | 0.76 | DPYD (0.62) | DPYDMAPTGAAALDH1A1ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285057-A2 | Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same | ENZO BIOCHEM, INC. (US) | 1988-10-05 | — | — | EP | disclosed |