Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696940 | 1.00 | DPYD (0.65) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL1916591 | 0.79 | DPYD (0.63) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL1228163 | 0.79 | DPYD (0.63) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL170251 | 0.79 | DPYD (1.00) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL23622048 | 0.77 | DPYD (0.45) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL21345242 | 0.77 | KDM3B (0.47) | DPYDMAPTGAAALDH1A1CYP2A6 | |
| SCHEMBL6374591 | 0.76 | DPYD (0.59) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL6374582 | 0.76 | DPYD (0.59) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL15798473 | 0.76 | DPYD (0.62) | DPYDMAPTGAAALDH1A1ATAD2 | |
| SCHEMBL65892 | 0.76 | DPYD (0.62) | DPYDMAPTGAAALDH1A1ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 863 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026106497-A2 | FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION | SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) | 2026-05-21 | — | — | WO | claimed |
| US-12630851-B2 | Polynucleotide modification methods | OXFORD NANOPORE TECHNOLOGIES PLC (GB) | 2026-05-19 | — | — | US | claimed |
| US-20250369027-A1 | SUBSTRATE CLEAVAGE FOR NUCLEIC ACID SYNTHESIS | TWIST BIOSCIENCE CORP (US) | 2025-12-04 | — | — | US | claimed |
| US-20250327068-A1 | Method for Generation of a Nucleic Acid Library | MILTENYI BIOTEC BV & CO KG (DE) | 2025-10-23 | — | — | US | claimed |
| EP-4569132-A2 | METHOD, KIT AND SYSTEM FOR END LABELING OF NUCLEIC ACIDS | Chen, Cheng-Yao (TW) | 2025-06-18 | — | — | EP | claimed |
| WO-2025111452-A2 | CHEMICAL MODIFICATIONS IN PEgRNA and ngRNAs | PRIME MEDICINE, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| CN-120077136-A | SiRNA and drug for inhibiting Amyloid Precursor Protein (APP) gene expression and application thereof | 广州必贝特医药股份有限公司 | 2025-05-30 | — | — | CN | claimed |
| WO-2025111430-A1 | CHEMICAL MODIFICATIONS IN mRNA POLY(A) TAIL | PRIME MEDICINE, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| CN-119948172-A | Methods, kits and systems for nucleic acid end labeling | 陈呈尧 | 2025-05-06 | — | — | CN | claimed |
| CN-119286094-B | Graphite tailing/polyethylene composite material and preparation method thereof | 黑龙江省朴澍科技有限责任公司 | 2025-05-06 | — | — | CN | claimed |
| EP-1281757-A1 | Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids | Direvo Biotech AG (DE) | 2003-02-05 | — | — | EP | claimed |
| WO-2002083123-A1 | AURONES AS TELOMERASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2002-10-24 | — | — | WO | claimed |
| US-6369237-B1 | ENZYME INHIBITORS OF DNA GLYCOLASE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-04-09 | — | — | US | claimed |
| US-20020026053-A1 | Novel 3-(substituted) -2- indolinones compounds and use thereof as inhibitors of protein kinase activity | TANG PENG CHO (US) | 2002-02-28 | — | — | US | claimed |
| US-20010007033-A1 | Novel 3-(substituted)-2-indolinones compounds and use thereof as inhibitors of protein kinase activity | SUGEN, INC. | 2001-07-05 | — | — | US | claimed |
| WO-1999050447-A1 | METHOD AND NUCLEIC ACID COMPOUND FOR BREAKING DOWN NUCLEIC ACID MOLECULES SYNTHESIZED $i(IN VITRO) | MIRA DIAGNOSTIKA GMBH (DE) | 1999-10-07 | — | — | WO | claimed |
| WO-1998039334-A9 | DNA GLYCOSYLASE INHIBITORS, AND USES RELATED THERETO | — | 1999-02-18 | — | — | WO | claimed |
| WO-1998039334-A1 | DNA GLYCOSYLASE INHIBITORS, AND USES RELATED THERETO | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1998-09-11 | — | — | WO | claimed |
| WO-1993017651-A2 | ANTIVIRAL NUCLEOSIDE ANALOGUES, THEIR PRODUCTION AND USE | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 1993-09-16 | — | — | WO | claimed |
| US-5118800-A | Oligonucleotides possessing a primary amino group in the terminal nucleotide | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020026053-A1 | Novel 3-(substituted) -2- indolinones compounds and use thereof as inhibitors of protein kinase activity | MAP3K20, SBK3, MAP4K2 | DPYD 807/4885MAPT 3371/4885GAA 2413/4885 |
| US-12630851-B2 | Polynucleotide modification methods | PNP, NT5C3B, UNG | DPYD 43/4885MAPT 3328/4885GAA 1181/4885 |
| US-20010007033-A1 | Novel 3-(substituted)-2-indolinones compounds and use thereof as inhibitors of protein kinase activity | SBK3, MAP4K2, MAP3K20 | DPYD 797/4885MAPT 3376/4885GAA 2450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.