SCHEMBL4501771

SCHEMBL4501771

CC(N)Cc1ccc2cc[nH]c2c1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.54
HTR2C P28335 1/20 0.54
HTR2B P41595 1/20 0.54
BACE1 P56817 2/20 0.49
PNMT P11086 2/20 0.47
TAAR1 Q96RJ0 2/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
ACACB O00763 1/20 0.44
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
AHR P35869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Acid SCHEMBL31609215 0.87 BLM (0.47) HTR2AHTR2CHTR2BBACE1ACACB
SCHEMBL2553783 0.86 HTR2A (0.54) HTR2AHTR2CHTR2BPNMTTAAR1
SCHEMBL13230520 0.86 ACACB (0.46) BACE1ACACBMEN1POLBMAPK1
Indole SCHEMBL25347206 0.83 HTR2A (0.59) HTR2AHTR2CHTR2BPNMTTAAR1
SCHEMBL6744093 0.80 SLC6A4 (0.44) BACE1SLC6A4ACACBMEN1POLB
SCHEMBL20458865 0.79 ACACB (0.44) BACE1ACACBMEN1POLBMAPK1
SCHEMBL5321639 0.78 SLC7A5 (0.54) HTR2ABACE1ACACB
SCHEMBL26008228 0.78 SLC7A5 (0.54) HTR2ABACE1ACACB
SCHEMBL13230548 0.76 BACE1 (0.49) BACE1ACACBMEN1POLBMAPK1
SCHEMBL879350 0.76 BACE1 (0.51) BACE1MEN1POLBMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-221921873-U High-speed high-mobility high-precision reconnaissance satellite transmission gear tooth 沈阳戈达德智能装备科技有限公司 2024-10-29 CN claimed
CN-117628145-A Design method for high-speed high-mobility high-precision reconnaissance satellite transmission gear teeth 沈阳戈达德智能装备科技有限公司 2024-03-01 CN claimed
CN-117042779-A Probiotic treatment method for improving human health 种子保健有限公司 2023-11-10 CN claimed
CN-114536584-B Moving bed biomembrane suspension carrier for sewage treatment and preparation method thereof 青岛思普润水处理股份有限公司 2023-08-22 CN claimed
CN-114857000-B Vortex air compressor design and manufacturing method for improving engagement tightness of dynamic and static discs 浙江省机电设计研究院有限公司 2023-08-22 CN claimed
CN-113761678-B Cylindrical grinding flutter general model and stability analysis method 上海机床厂有限公司 2023-06-20 CN claimed
CN-114888368-A Method for improving cutting machining precision of CG internal threads made of stainless steel material 贵州永红航空机械有限责任公司 2022-08-12 CN claimed
CN-114857000-A Design and manufacturing method of vortex air compressor for improving meshing sealing performance of moving disc and static disc 浙江省机电设计研究院有限公司 2022-08-05 CN claimed
CN-114536584-A Moving bed biofilm suspension carrier for sewage treatment and preparation method thereof 青岛思普润水处理股份有限公司 2022-05-27 CN claimed
EP-4739777-A1 TRANSMISSIBLE ELEMENTS COMPRISING PATHWAY MODIFICATION SYSTEMS AND EXOGENOUS NUCLEIC ACIDS FOR THE PRODUCTION OF MOLECULES OF INTEREST SNIPR Biome ApS (DK) 2026-05-13 EP disclosed
US-12621435-B2 Constraints on reference picture lists BYTEDANCE INC. (US) 2026-05-05 US disclosed
US-12566745-B1 Splitting a node of a tree data structure Vast Data Ltd. (IL) 2026-03-03 US disclosed
EP-4268242-B1 NONPARAMETRIC GLUCOSE PREDICTORS DEXCOM INC (US) 2025-12-17 EP disclosed
US-12483694-B2 Sublayers information in video coding BYTEDANCE INC. (US) 2025-11-25 US disclosed
US-20070043048-A1 2-Aminopyrimidine derivatives and their medical use NOVARTIS AG (CH) 2007-02-22 US disclosed
CN-1802357-A 2-aminopyrimidine derivatives and their medical use NOVARTIS AG (CH) 2006-07-12 CN disclosed
EP-1615898-A1 2-AMINOPYRIMIDINE DERIVATIVES AND THEIR MEDICAL USE Novartis AG (CH) 2006-01-18 EP disclosed
WO-2004089913-A1 AMINOPYRIMIDINE DERIVATIVES AND THEIR MEDICAL USE NOVARTIS AG (CH) 2004-10-21 WO disclosed
US-20040167158-A1 Heterocyclic compounds for the treatment of migraine NPS ALLELIX BIOPHARMACEUTICALS, INC. (CA) 2004-08-26 US disclosed
US-6716837-B1 INDOLE AND INDAZOLE COMPOUNDS NPS ALLELIX BIOPHARMACEUTICALS, INC. (CA) 2004-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043048-A1 2-Aminopyrimidine derivatives and their medical use TPMT, IKBKB, CHUK HTR2A 3876/4885HTR2C 3801/4885HTR2B 4009/4885
US-20040167158-A1 Heterocyclic compounds for the treatment of migraine SCN7A, CNR2, HTR7 HTR2A 294/4885HTR2C 116/4885HTR2B 99/4885
US-12621435-B2 Constraints on reference picture lists VSIR, SLIRP, NOTCH1 HTR2A 2074/4885HTR2C 2919/4885HTR2B 3010/4885
US-12566745-B1 Splitting a node of a tree data structure SMC2, SMC4, MCM2 HTR2A 3214/4885HTR2C 2661/4885HTR2B 3079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.