SCHEMBL4501913

SCHEMBL4501913

CO[Si](CCNC(=O)c1ccc(C(=O)c2ccccc2)cc1)(OC)OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.57
LMNA P02545 2/20 0.55
POLB P06746 1/20 0.55
SMN1; SMN2 Q16637 4/20 0.51
ALDH1A1 P00352 4/20 0.51
RAB9A P51151 6/20 0.50
NPC1 O15118 5/20 0.50
PRSS1 P07477 1/20 0.50
CTSG P08311 1/20 0.50
CTRB1 P17538 1/20 0.50
CMA1 P23946 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
NAAA Q02083 1/20 0.49
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
ATM Q13315 1/20 0.48
DRD2 P14416 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4496407 0.91 HPGD (0.55) HPGDLMNAPOLBSMN1; SMN2ALDH1A1
SCHEMBL2007944 0.84 NAAA (0.59) HPGDLMNAPOLBSMN1; SMN2ALDH1A1
SCHEMBL2849812 0.83 NPC1 (0.60) LMNAPOLBSMN1; SMN2ALDH1A1RAB9A
SCHEMBL17226037 0.79 NAAA (0.65) HPGDLMNAPOLBSMN1; SMN2ALDH1A1
SCHEMBL12927089 0.79 HDAC3 (0.50) HPGDLMNAPOLBSMN1; SMN2ALDH1A1
SCHEMBL13861935 0.78 DRD2 (0.63) SMN1; SMN2ALDH1A1RAB9ANPC1NAAA
SCHEMBL22373762 0.78 SMN1; SMN2 (0.54) HPGDLMNAPOLBSMN1; SMN2ALDH1A1
SCHEMBL14032187 0.78 HPGD (0.60) HPGDLMNAPOLBSMN1; SMN2ALDH1A1
SCHEMBL11350660 0.78 HPGD (0.59) HPGDLMNAPOLBSMN1; SMN2ALDH1A1
SCHEMBL9980885 0.77 NAAA (0.55) HPGDLMNAPOLBSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12599322-B2 Method for an analyte sensor cover-membrane preparation ROCHE DIABETES CARE, INC. (US) 2026-04-14 US disclosed
EP-3735903-B1 METHOD FOR AN ANALYTE SENSOR COVER-MEMBRANE PREPARATION ROCHE DIABETES CARE GMBH (DE) 2025-11-05 EP disclosed
EP-3359580-B1 POLYMER HAVING ANTIMICROBIAL AND/OR ANTIFOULING PROPERTIES UNIV FREIBURG ALBERT LUDWIGS (DE) 2022-03-30 EP disclosed
US-20220054059-A1 METHOD FOR AN ANALYTE SENSOR COVER-MEMBRANE PREPARATION ROCHE DIABETES CARE, INC. 2022-02-24 US disclosed
US-10889726-B2 Polymer having antimicrobial and/or antifouling properties ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2021-01-12 US disclosed
WO-2020225190-A1 METHOD FOR AN ANALYTE SENSOR COVER-MEMBRANE PREPARATION F. HOFFMANN-LA ROCHE AG (CH) 2020-11-12 WO disclosed
EP-3735903-A1 METHOD FOR AN ANALYTE SENSOR COVER-MEMBRANE PREPARATION Roche Diabetes Care GmbH (DE) 2020-11-11 EP disclosed
EP-2822986-B1 SYNTHESIS AND MICRO-/NANOSTRUCTURING OF SURFACE-ATTACHED CROSSLINKED ANTIMICROBIAL AND/OR ANTIBIOFOULING POLYMER NETWORKS UNIV FREIBURG (DE) 2019-10-30 EP disclosed
US-10259915-B2 Synthesis and micro-/nanostructuring of surface-attached crosslinked antimicrobial and/or antibiofouling polymer networks UNIVERSITATSKLINIKUM FREIBURG (DE) 2019-04-16 US disclosed
US-20180327607-A1 POLYMER HAVING ANTIMICROBIAL AND/OR ANTIFOULING PROPERTIES ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2018-11-15 US disclosed
WO-2013132066-A2 SYNTHESIS AND MICRO-/NANOSTRUCTURING OF SURFACE-ATTACHED CROSSLINKED ANTIMICROBIAL AND/OR ANTIBIOFOULING POLYMER NETWORKS Universitätsklinikum Freiburg (DE) 2013-09-12 WO disclosed
EP-2636693-A1 Synthesis and micro-/nanostructuring of surface-attached crosslinked antimicrobial and/or antibiofouling polymer networks Universitätsklinikum Freiburg (DE) 2013-09-11 EP disclosed
EP-2471827-B1 Covalently attached antimicrobial polymers UNIVERSITAETSKLINIKUM FREIBURG (DE) 2013-09-04 EP disclosed
WO-2012089617-A1 COVALENTLY ATTACHED ANTIMICROBIAL POLYMERS Universitätsklinikum Freiburg (DE) 2012-07-05 WO disclosed
EP-2471827-A1 Covalently attached antimicrobial polymers Universitätsklinikum Freiburg (DE) 2012-07-04 EP disclosed
EP-2117728-A2 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS SurModics, Inc. (US) 2009-11-18 EP disclosed
WO-2008103668-A2 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS SURMODICS, INC. (US) 2008-08-28 WO disclosed
US-20070141365-A1 Silane Coating Compositions, Coating Systems, and Methods Surmodics Coatings, LLC 2007-06-21 US disclosed
US-20070054127-A1 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS Surmodics Coatings, LLC 2007-03-08 US disclosed
WO-2007025059-A1 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS SURMODICS, INC. (US) 2007-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10259915-B2 Synthesis and micro-/nanostructuring of surface-attached crosslinked antimicrobial and/or antibiofouling polymer networks CUTA, CLSPN, DSTN HPGD 3427/4885LMNA 4008/4885POLB 794/4885
US-12599322-B2 Method for an analyte sensor cover-membrane preparation F10, S100A10, EPCAM HPGD 655/4885LMNA 622/4885POLB 3382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.