Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 12/20 | 0.89 |
| ▸ | ACVRL1 | P37023 | 12/20 | 0.89 |
| ▸ | RET | P07949 | 5/20 | 0.89 |
| ▸ | ROS1 | P08922 | 5/20 | 0.89 |
| ▸ | MET | P08581 | 2/20 | 0.89 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.77 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.77 |
| ▸ | IGF1R | P08069 | 7/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15996407 | 1.00 | NTRK1 (0.89) | NTRK1ACVRL1RETROS1MET | |
| SCHEMBL438526 | 1.00 | NTRK1 (0.89) | NTRK1ACVRL1RETROS1MET | |
| SCHEMBL15996586 | 0.97 | NTRK1 (0.84) | NTRK1ACVRL1RETROS1MET | |
| SCHEMBL16437781 | 0.94 | NTRK1 (1.00) | NTRK1ACVRL1RETROS1MET | |
| SCHEMBL438665 | 0.94 | NTRK1 (1.00) | NTRK1ACVRL1RETROS1MET | |
| SCHEMBL14733171 | 0.93 | NTRK1 (0.77) | NTRK1ACVRL1RETROS1MET | |
| SCHEMBL3458271 | 0.92 | NTRK1 (0.86) | NTRK1ACVRL1RETROS1MET | |
| SCHEMBL14719264 | 0.92 | NTRK1 (0.86) | NTRK1ACVRL1RETROS1MET | |
| SCHEMBL3459821 | 0.91 | NTRK1 (0.74) | NTRK1ACVRL1RETROS1MET | |
| SCHEMBL14719587 | 0.91 | NTRK1 (0.74) | NTRK1ACVRL1RETROS1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387587-A1 | COMPOSITIONS | Symrise AG (DE) | 2024-06-26 | — | — | EP | claimed |
| WO-2024078679-A1 | A FRAGRANCE MIXTURE (VI) | SYMRISE AG (DE) | 2024-04-18 | — | — | WO | claimed |
| WO-2024051922-A1 | A FRAGRANCE MIXTURE (III) | SYMRISE AG (DE) | 2024-03-14 | — | — | WO | claimed |
| WO-2024027922-A1 | A FRAGRANCE MIXTURE (II) | SYMRISE AG (DE) | 2024-02-08 | — | — | WO | claimed |
| WO-2023232243-A1 | A FRAGRANCE MIXTURE (V) | SYMRISE AG (DE) | 2023-12-07 | — | — | WO | claimed |
| WO-2023232242-A1 | FRAGRANCE MIXTURE | SYMRISE AG (DE) | 2023-12-07 | — | — | WO | claimed |
| WO-2023213386-A1 | A FRAGRANCE MIXTURE (V) | SYMRISE AG (DE) | 2023-11-09 | — | — | WO | claimed |
| WO-2023147852-A1 | COMPOSITIONS (III) | SYMRISE AG (DE) | 2023-08-10 | — | — | WO | claimed |
| WO-2023147874-A1 | A FRAGRANCE MIXTURE | SYMRISE AG (DE) | 2023-08-10 | — | — | WO | claimed |
| WO-2023083445-A1 | COMPOSITIONS COMPRISING TRPM8 AGONISTIC COOLING AGENTS | SYMRISE AG (DE) | 2023-05-19 | — | — | WO | claimed |
| WO-2023021012-A1 | COMPOSITIONS | SYMRISE AG (DE) | 2023-02-23 | — | — | WO | claimed |
| US-11352587-B2 | Fragrance mixtures | SYMRISE AG (DE) | 2022-06-07 | — | — | US | claimed |
| US-11116712-B2 | Fragrance composition | SYMRISE AG (DE) | 2021-09-14 | — | — | US | claimed |
| EP-2262807-B1 | NOVEL TYROSINE KINASE INHIBITORS | CHEMBRIDGE CORP (US) | 2015-08-12 | — | — | EP | claimed |
| EP-1848702-A2 | PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS | Flexitral, Inc. (US) | 2007-10-31 | — | — | EP | claimed |
| US-20060205632-A1 | Pro-fragrance and pro-flavorant compositions | FLEXITRAL, INC. | 2006-09-14 | — | — | US | claimed |
| WO-2006085048-A2 | PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS | FLEXITRAL, INC. (US) | 2006-08-17 | — | — | WO | claimed |
| US-12023396-B2 | Flavour and fragrance compositions comprising acetophenone derivatives | SYMRISE AG (DE) | 2024-07-02 | — | — | US | disclosed |
| WO-1999016802-A1 | COPOLYMERIC COMPOUNDS COMPRISING ONE OR MORE ACTIVE ALDEHYDE MONOMERIC UNIT | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-08 | — | — | WO | disclosed |
| WO-1999016803-A1 | CO-POLYMERIC COMPOUNDS COMPRISING ONE OR MORE ACTIVE ALDEHYDE MONOMERIC UNIT | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12023396-B2 | Flavour and fragrance compositions comprising acetophenone derivatives | FAAH2, ADH5, NISCH | NTRK1 3296/4885ACVRL1 1917/4885RET 4275/4885 |
| US-11352587-B2 | Fragrance mixtures | DHCR24, FAM120A, TRPA1 | NTRK1 4014/4885ACVRL1 2603/4885RET 3527/4885 |
| US-11116712-B2 | Fragrance composition | NISCH, CUTA, CYP1B1 | NTRK1 3776/4885ACVRL1 4034/4885RET 4595/4885 |
| US-20060205632-A1 | Pro-fragrance and pro-flavorant compositions | TAS2R10, TAS2R9, OR10J3 | NTRK1 3356/4885ACVRL1 2483/4885RET 911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.