SCHEMBL450274

SCHEMBL450274

C=C(C(=O)O)C(F)(F)C(F)(F)C(F)(F)CF

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5360465 0.94 THRB (0.32) TET2
SCHEMBL4340451 0.92 THRB (0.35)
SCHEMBL5412510 0.92 THRB (0.35)
SCHEMBL561206 0.86 TET2 (0.33) TET2
SCHEMBL15413473 0.81
SCHEMBL4313157 0.81 TET2 (0.31) TET2
SCHEMBL2806113 0.79
SCHEMBL10657421 0.78 TET2 (0.32) TET2
SCHEMBL1635423 0.77 THRB (0.44) TET2
SCHEMBL3850818 0.75 THRB (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4182737-B1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2024-07-03 EP claimed
CN-117683423-A Self-cleaning coating for waterproof coiled material, waterproof coiled material and preparation method thereof 江苏凯伦建材股份有限公司 2024-03-12 CN claimed
EP-3359992-B1 METHOD TO PRODUCE POLYMER CONVERTER FOR CONNECTING OPTICAL FIBRES WOJSKOWA AKADEMIA TECHNICZNA IM JAROSLAWA DABROWSKIEGO (PL) 2023-07-12 EP claimed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP claimed
EP-2091985-B1 REVERSIBLE MICELLES AND APPLICATIONS FOR THEIR USE UNIV LEEDS (GB) 2013-02-20 EP claimed
EP-2021388-B1 MICHAEL ADDITION ADDUCTS AS ADDITIVES FOR PAPER AND PAPERMAKING HERCULES INC (US) 2012-03-21 EP claimed
EP-1189622-B1 ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS GENZYME CORP (US) 2007-07-25 EP claimed
EP-0915705-B1 IONIC POLYMERS AS ANTI-INFECTIVE AGENTS GENZYME CORP (US) 2007-01-10 EP claimed
EP-1014999-B1 CATIONIC POLYMERS AS TOXIN-BINDING AGENTS GENZYME CORP (US) 2004-12-08 EP claimed
EP-1289451-B1 PROSTHETIC CORNEA CORNEAL IND (FR) 2004-12-01 EP claimed
EP-0835294-B1 LIGHT DIFFUSING ADHESIVE MINNESOTA MINING & MFG (US) 2003-01-29 EP claimed
US-20020114777-A1 Ionic polymers as anti-infective agents GELTEX PHARMACEUTICALS, INC. (US) 2002-08-22 US claimed
EP-0981418-B1 INTRAOCULAR LENS TUMBLING PROCESS USING COATED BEADS BAUSCH & LOMB SURGICAL INC (US) 2002-06-26 EP claimed
US-6395777-B2 ORGANONITROGEN POLYMERS GELTEX PHARMACEUTICALS, INC. 2002-05-28 US claimed
US-20010053794-A1 Ionic polymers as anti-infective agents GENZYME CORPORATION 2001-12-20 US claimed
EP-1015000-A1 ANTIVIRAL POLYMERS COMPRISING ACID FUNCTIONAL AND HYDROPHOBIC GROUPS GELTEX PHARMACEUTICALS, INC. (US) 2000-07-05 EP claimed
EP-0915705-A1 IONIC POLYMERS AS ANTI-INFECTIVE AGENTS GELTEX PHARMACEUTICALS, INC. (US) 1999-05-19 EP claimed
WO-1999015187-A1 ANTIVIRAL POLYMERS COMPRISING ACID FUNCTIONAL AND HYDROPHOBIC GROUPS GELTEX PHARMACEUTICALS, INC. (US) 1999-04-01 WO claimed
WO-1997049413-A1 IONIC POLYMERS AS ANTI-INFECTIVE AGENTS GELTEX PHARMACEUTICALS, INC. (US) 1997-12-31 WO claimed
EP-0036272-B1 PERMANENT DENTAL RESTORATIVE COMPOSITIONS AND METHODS OF USING THEM ROHM AND HAAS COMPANY (US) 1985-01-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010053794-A1 Ionic polymers as anti-infective agents PAM, ARG1, PIGS TET2 1234/4885
US-20020114777-A1 Ionic polymers as anti-infective agents PAM, ARG1, PIGS TET2 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.