SCHEMBL4502874

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4501189	0.78	MAPT (0.43)	MLKLKMT2AMEN1ALDH1A1LMNA
	SCHEMBL1379087	0.75	DAO (0.41)	DAODDOMLKLKMT2AMEN1
	SCHEMBL4511745	0.73	MTNR1A (0.52)	KMT2AMEN1ALDH1A1LMNAHPGD
	SCHEMBL1376601	0.72	KIF11 (0.33)	ALDH1A1LMNAHPGDMAPTCYP19A1
	SCHEMBL4500952	0.72	PIM1 (0.39)	CYP19A1
	SCHEMBL4759753	0.71	MTNR1A (0.64)	POLBALDH1A1HPGDHSD17B10KDM4E
	SCHEMBL3287746	0.70	DAO (0.41)	DAODDOMLKLKMT2AMEN1
	SCHEMBL1378443	0.70	MTNR1A (0.47)	KMT2AMEN1HPGDCYP19A1TSHR
	SCHEMBL4485409	0.69	MTNR1A (0.49)	KMT2AMEN1ALDH1A1HPGDHSD17B10
	SCHEMBL4506993	0.69	MTNR1A (0.55)	POLBALDH1A1HPGDHSD17B10CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.