SCHEMBL4501189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1379874	0.87	MTNR1A (0.49)	MAPTLMNAHTTALDH1A1CYP19A1
	SCHEMBL1376601	0.84	KIF11 (0.33)	MAPTLMNAHTTALDH1A1CYP19A1
	SCHEMBL4502874	0.78	DAO (0.39)	MAPTLMNAHTTMLKLKMT2A
	SCHEMBL1376806	0.77	MTNR1A (0.47)	KMT2AALDH1A1KDM4ECYP1A2CYP3A4
	SCHEMBL4759753	0.77	MTNR1A (0.64)	ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6
	SCHEMBL1379412	0.77	MTNR1A (0.59)	KMT2AALDH1A1CYP19A1KDM4ECYP1A2
	SCHEMBL4507265	0.77	MLKL (0.40)	MAPTLMNAHTTMLKLKMT2A
	SCHEMBL4500952	0.73	PIM1 (0.39)	CYP19A1PIM1
	SCHEMBL1378443	0.73	MTNR1A (0.47)	KMT2ACYP19A1CYP1A2CYP3A4CYP2C9
	SCHEMBL8239481	0.72	MTNR1A (0.51)	LMNAKMT2AALDH1A1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.