SCHEMBL450333

SCHEMBL450333

COC1=CC(=O)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125003 0.84
SCHEMBL11694300 0.80
Bicarbonate SCHEMBL9807679 0.77 MAPT (0.51)
SCHEMBL1021859 0.75
SCHEMBL7362200 0.75 MAPT (0.42)
SCHEMBL13863801 0.74 CA1 (0.37)
SCHEMBL2736475 0.74 USP2 (0.33)
SCHEMBL6639439 0.74 GLA (0.38)
SCHEMBL3643718 0.71 PLA2G7 (0.36)
SCHEMBL10248293 0.71 LMNA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7655814-B2 Reacting a cyclopentene having an oxo group and/or hydroxyl groups with a halogen (bromine) in the presence of an aqueous base (sodium hydroxide/water); neutralization by hydrochloric acid; oxidation; cost efficiency;simplification; industrial scale; dyes; drugs; agriculture; intermediates FUJIFILM CORPORATION (JP) 2010-02-02 US claimed
US-20080293822-A1 Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use ETHISMOS RESEARCH, INC. 2008-11-27 US claimed
US-20080269348-A1 Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use ETHISMOS RESEARCH, INC. 2008-10-30 US claimed
US-20060224022-A1 Process for producing croconic acid or salt thereof FUJI PHOTO FILM CO., LTD. 2006-10-05 US claimed
EP-1707552-A1 Process for producing croconic acid or salt thereof FUJI PHOTO FILM CO., LTD. (JP) 2006-10-04 EP claimed
EP-4547638-A1 ORGANIC COMPOUNDS Givaudan SA (CH) 2025-05-07 EP disclosed
WO-2024242120-A1 PATTERN FORMING METHOD AND PROCESSING LIQUID FOR METAL COMPOUND-CONTAINING FILM 東京応化工業株式会社 2024-11-28 WO disclosed
WO-2024003176-A1 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-01-04 WO disclosed
US-10375956-B2 Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof SYNGENTA LIMITED (GB) 2019-08-13 US disclosed
EP-3004063-B1 HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF SYNGENTA LTD (GB) 2018-07-18 EP disclosed
US-9890139-B2 CYP17 inhibitors/antiandrogens ORION CORPORATION (FI) 2018-02-13 US disclosed
US-9394279-B2 Anti-viral compounds ABBVIE INC. (US) 2016-07-19 US disclosed
EP-1061076-A1 N-ACYL CYCLIC AMINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2000-12-20 EP disclosed
US-6140333-A FOR TREATMENT AND/OR PROPHYLAXIS OF DISEASES INCLUDE SUCH RESPIRATORY DISEASES AS CHRONIC OBSTRUCTIVE PULMONARY DISEASES, CHRONIC BRONCHITIS, ASTHMA, CHRONIC RESPIRATORY OBSTRUCTION, PULMONARY FIBROSIS, PULMONARY EMPHYSEMA BANYU PHARMACEUTICAL CO LTD (JP) 2000-10-31 US disclosed
WO-2000056702-A1 RESORCINOL DERIVATIVES PFIZER INC. (US) 2000-09-28 WO disclosed
US-5217982-A Compounds having antihypertensive properties RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1993-06-08 US disclosed
US-5071871-A Pharmaceutically useful benzo(β)pyranes and pyranopyridines SANDOZ LTD. (CH) 1991-12-10 US disclosed
US-4058666-A INSECTICIDE ZOECON CORPORATION (US) 1977-11-15 US disclosed
US-4006188-A Cycloalkenones ZOECON CORPORATION (US) 1977-02-01 US disclosed
US-4000174-A NOVEL COMPOUNDS ZOECON CORPORATION (US) 1976-12-28 US disclosed