Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP5C | P53041 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854408 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL4506840 | 0.70 | SMN1; SMN2 (0.35) | SMN1; SMN2GBA1 | |
| SCHEMBL15861023 | 0.67 | GBA1 (0.35) | GBA1 | |
| SCHEMBL12310110 | 0.67 | GBA1 (0.35) | GBA1 | |
| SCHEMBL4915956 | 0.66 | — | — | |
| Propylene Oxide SCHEMBL4803587 | 0.66 | SMN1; SMN2 (0.45) | PPP5CSMN1; SMN2GBA1 | |
| SCHEMBL8977172 | 0.66 | PTAFR (0.39) | SMN1; SMN2GBA1 | |
| SCHEMBL17898696 | 0.66 | FUCA1 (0.47) | GBA1 | |
| SCHEMBL3027705 | 0.65 | SMN1; SMN2 (0.43) | PPP5CSMN1; SMN2GBA1 | |
| SCHEMBL18542281 | 0.65 | SMN1; SMN2 (0.49) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7518003-B2 | Production process of tetrahydropyran compound and tetrahydropyran compound produced by the production process | SHOWA DENKO K.K. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20080139828-A1 | Reacting 3,4-dihydro-2-alkoxy-2H-pyran with hydrogen in the presence of a catalyst under acidic condition; Grignard reaction solvent or polymer solvent | SHOWA DENKO K.K. (JP) | 2008-06-12 | — | — | US | disclosed |
| CN-101068800-A | Method for producing tetrahydropyran compound and tetrahydropyran compound produced by the production method | SHOWA DENKO KK (JP) | 2007-11-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139828-A1 | Reacting 3,4-dihydro-2-alkoxy-2H-pyran with hydrogen in the presence of a catalyst under acidic condition; Grignard reaction solvent or polymer solvent | HPD, ACR, GRHPR | PPP5C 4388/4885SMN1; SMN2 4462/4885GBA1 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.