Known targets — ChEMBL curated mechanism
BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 8/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nicotinyl Alcohol SCHEMBL4511513 | 0.86 | NAPRT (0.61) | NAPRTSMN1; SMN2TSHRNAMPTCYP2C9 | |
| Hypochlorous Acid SCHEMBL7837490 | 0.79 | CYP1A2 (0.54) | NAPRTCYP2C9TDP1 | |
| SCHEMBL17432 | 0.79 | — | — | |
| Acetic Acid SCHEMBL28816937 | 0.78 | NAPRT (0.59) | NAPRTCYP2C9KMT2ATBXAS1TDP1 | |
| SCHEMBL769776 | 0.78 | NAPRT (0.58) | NAPRTNAMPTTBXAS1 | |
| Bromide SCHEMBL4240042 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL2076896 | 0.77 | — | — | |
| Phosphine SCHEMBL18110397 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL18044 | 0.77 | — | — | |
| Ammonia Solution, Strong SCHEMBL28235189 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1875000-B | Method for producing bactericidal pyridine compound and bactericidal pyridine compound | TAMA KAGAKU KOGYO CO LTD | 2011-05-04 | — | — | CN | disclosed |
| US-7612097-B2 | Method for producing bactericidal pyridine compound and bactericidal pyridine compound | TAMA KAGAKU KOGYO CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-20070099961-A1 | Method for producing bactericidal pyridine compound and bactericidal pyridine compound | Kourai, Hiroki (JP) | 2007-05-03 | — | — | US | disclosed |
| CN-1875000-A | Method for producing bactericidal pyridine compound and bactericidal pyridine compound | TAMA KAGAKU KOGYO CO LTD (JP) | 2006-12-06 | — | — | CN | disclosed |
| EP-1683787-A1 | METHOD FOR PRODUCING BACTERICIDAL PYRIDINE COMPOUND AND BACTERICIDAL PYRIDINE COMPOUND | Tama Kagaku Kogyo Co., Ltd. (JP) | 2006-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099961-A1 | Method for producing bactericidal pyridine compound and bactericidal pyridine compound | BLVRB, CBR3, TLR7 | NAPRT 2474/4885SMN1; SMN2 4476/4885TSHR 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.