Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753194 | 0.86 | SORT1 (0.53) | SORT1RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL15966082 | 0.81 | ADORA3 (0.50) | SORT1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20263290 | 0.80 | SORT1 (0.48) | SORT1RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL25346779 | 0.80 | RAB9A (0.62) | SORT1RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL22548707 | 0.80 | RAB9A (0.43) | SORT1RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL17356339 | 0.78 | SORT1 (0.82) | SORT1RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL6469040 | 0.77 | LCK (0.46) | SORT1 | |
| SCHEMBL12465535 | 0.76 | RAB9A (0.40) | SORT1RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL15903355 | 0.75 | SORT1 (1.00) | SORT1RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL21640986 | 0.75 | AHR (0.47) | SORT1RAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | SORT1 1489/4885RAB9A 3368/4885NPC1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.