Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51349 | 0.85 | ALDH1A1 (0.61) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL5636034 | 0.83 | KLF10 (0.78) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL30124085 | 0.83 | KLF10 (0.78) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL5167762 | 0.83 | ALDH1A1 (0.59) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL22275799 | 0.83 | KLF10 (0.53) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL16405458 | 0.82 | ALDH1A1 (0.57) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL10233336 | 0.82 | ALDH1A1 (0.57) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL14297625 | 0.82 | EPHX2 (0.44) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL11344556 | 0.82 | ALDH1A1 (0.57) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL7979494 | 0.81 | KLF10 (0.47) | ALDH1A1ALOX15HSD17B10HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321625-B | Synthetic method for preparing benzoxazole compound from catechol compound, ammonium acetate and aldehyde compound | 湖南第一师范学院 | 2022-05-24 | — | — | CN | disclosed |
| CN-113321625-A | Synthetic method for preparing benzoxazole compound from catechol compound, ammonium acetate and aldehyde compound | 湖南第一师范学院 | 2021-08-31 | — | — | CN | disclosed |
| US-7638648-B2 | Compounds having selective cytochrome P450RAI-1 or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining the same | ALLERGAN INC. (US) | 2009-12-29 | — | — | US | disclosed |
| US-7638648-B2 | Compounds having selective cytochrome P450RAI-1 or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining the same | ALLERGAN INC. (US) | 2009-12-29 | — | — | US | disclosed |
| US-7638648-B2 | Compounds having selective cytochrome P450RAI-1 or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining the same | ALLERGAN INC. (US) | 2009-12-29 | — | — | US | disclosed |
| US-7468391-B2 | Methods for treating retinoid responsive disorders using selective inhibitors of CYP26A and CYP26B | ALLERGAN, INC. (US) | 2008-12-23 | — | — | US | disclosed |
| US-7468391-B2 | Methods for treating retinoid responsive disorders using selective inhibitors of CYP26A and CYP26B | ALLERGAN, INC. (US) | 2008-12-23 | — | — | US | disclosed |
| US-7468391-B2 | Methods for treating retinoid responsive disorders using selective inhibitors of CYP26A and CYP26B | ALLERGAN, INC. (US) | 2008-12-23 | — | — | US | disclosed |
| US-20080004455-A1 | Compounds having selective cytochrome P450RAI-1 or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining the same | ALLERGAN, INC. (US) | 2008-01-03 | — | — | US | disclosed |
| US-20080004455-A1 | Compounds having selective cytochrome P450RAI-1 or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining the same | ALLERGAN, INC. (US) | 2008-01-03 | — | — | US | disclosed |
| US-20050187298-A1 | Methods for treating retinoid responsive disorders using selective inhibitors of CYP26A and CYP26B | ALLERGAN, INC. (US) | 2005-08-25 | — | — | US | disclosed |
| US-20050176689-A1 | Compounds having selective cytochrome P450RAI-1 or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining the same | ALLERGAN, INC. | 2005-08-11 | — | — | US | disclosed |
| WO-2005058798-A2 | COMPOUNDS HAVING SELECTIVE CYTOCHROME P450RAI-1 OR SELECTIVE CYTOCHROME P450RAI-2 INHIBITORY ACTIVITY AND METHODS OF OBTAINING THE SAME | ALLERGAN, INC. (US) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058301-A1 | METHODS FOR TREATING RETINOID RESPONSIVE DISORDERS USING SELECTIVE INHIBITORS OF CYP26A AND CYP26B | ALLERGAN, INC. (US) | 2005-06-30 | — | — | WO | disclosed |
| US-5728861-A | REACTING OLEFIN WITH CARBON MONOXIDE AND HYDROGEN IN PRESENCE OF CATALYST CONTAINING GROUP VIII METAL AND SPECIFIED BISPHOSPHITE COMPOUND TO FORM ALDEHYDE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-03-17 | — | — | US | disclosed |
| US-5712403-A | CATALYST | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-01-27 | — | — | US | disclosed |
| US-5663403-A | CATALYSTS FOR HYDROFORMYLATION OR SIDE REACTION REDUCTION OF OLEFINS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5600032-A | OLIGOMERIZATION OF A CONJUGATED ALKADIENE IN PRESENCE OFPALLADIUM, PHOSPHORUS COMPLEX | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-02-04 | — | — | US | disclosed |
| EP-0009641-B1 | POLYPHOSPHAZENE POLYMERS CONTAINING ORTHO-DIFUNCTIONAL PHENYLENE SUBSTITUENTS AND METHOD FOR PREPARING SAME | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1983-03-23 | — | — | EP | disclosed |
| US-4221898-A | Polyphosphazene polymers containing ortho-difunctional phenylene substitutents | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176689-A1 | Compounds having selective cytochrome P450RAI-1 or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining the same | CYP1A2, CYP2A7, CYP3A7 | ALDH1A1 96/4885ALOX15 509/4885HSD17B10 74/4885 |
| US-20050187298-A1 | Methods for treating retinoid responsive disorders using selective inhibitors of CYP26A and CYP26B | CYP26B1, CYP2A6, CYP21A2 | ALDH1A1 108/4885ALOX15 779/4885HSD17B10 116/4885 |
| US-20080004455-A1 | Compounds having selective cytochrome P450RAI-1 or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining the same | CYP1A2, CYP2A7, CYP3A7 | ALDH1A1 96/4885ALOX15 509/4885HSD17B10 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.