SCHEMBL5636034

SCHEMBL5636034

CC(C)(C)c1ccc(O)c(CO)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLF10 Q13118 1/20 0.78
CYP2D6 P10635 5/20 0.65
ALDH1A1 P00352 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
HPGD P15428 1/20 0.59
ALOX15 P16050 1/20 0.59
HSD17B10 Q99714 1/20 0.59
PKM P14618 2/20 0.53
MAPT P10636 2/20 0.53
MEN1 O00255 1/20 0.53
GAA P10253 1/20 0.53
RECQL P46063 1/20 0.53
KMT2A Q03164 1/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2C19 P33261 1/20 0.53
ESR1 P03372 3/20 0.50
ESR2 Q92731 3/20 0.50
TSHR P16473 2/20 0.48
ADRB2 P07550 3/20 0.46
HIF1A Q16665 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30124085 1.00 KLF10 (0.78) KLF10CYP2D6ALDH1A1TDP1HPGD
Formaldehyde SCHEMBL18789320 0.94 KLF10 (0.70) KLF10CYP2D6ALDH1A1TDP1HPGD
SCHEMBL930410 0.88 KLF10 (1.00) KLF10CYP2D6ALDH1A1TDP1HPGD
SCHEMBL21002165 0.85 CYP2D6 (0.67) KLF10CYP2D6ALDH1A1TDP1HPGD
SCHEMBL51058 0.85 CYP2D6 (0.67) KLF10CYP2D6ALDH1A1TDP1HPGD
SCHEMBL28863770 0.84 CYP2D6 (0.61) KLF10CYP2D6ALDH1A1TDP1HPGD
SCHEMBL1229448 0.83 ESR1 (0.71) KLF10CYP2D6ALDH1A1TDP1HPGD
SCHEMBL4508763 0.83 ALDH1A1 (0.59) KLF10CYP2D6ALDH1A1TDP1HPGD
SCHEMBL22275799 0.83 KLF10 (0.53) KLF10CYP2D6ALDH1A1TDP1HPGD
SCHEMBL15290876 0.82 KLF10 (0.70) KLF10CYP2D6TDP1PKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535999-A Pressure-sensitive adhesive tape 江苏晶华新材料科技有限公司 2023-08-04 CN claimed
US-4259464-A CURING AGENTS, EMULSIFIERS, DEMULSIFIERS, DETERGENTS, BACTERICIDES PETROLITE CORPORATION (US) 1981-03-31 US claimed
CN-116535999-A Pressure-sensitive adhesive tape 江苏晶华新材料科技有限公司 2023-08-04 CN disclosed
CN-113820920-B Photosensitive resin composition, method for producing cured relief pattern, and semiconductor device 旭化成株式会社 2023-07-04 CN disclosed
US-11548850-B2 Development of a cofilin inhibitor for the treatment of hemorrhagic brain injury-induced neuroinflammation THE UNIVERSITY OF TOLEDO (US) 2023-01-10 US disclosed
CN-110088680-B Double-layer photosensitive layer roll 旭化成株式会社 2022-12-30 CN disclosed
CN-115447033-A Mold moistening resin for semiconductor packaging mold and application thereof 天津德高化成新材料股份有限公司 2022-12-09 CN disclosed
CN-115185157-A Photosensitive resin composition, method for producing cured relief pattern, and semiconductor device 旭化成株式会社 2022-10-14 CN disclosed
CN-114302885-A Calixarene compound and use thereof 维也纳大学 2022-04-08 CN disclosed
CN-109153841-B Resin composition 东丽株式会社 2021-12-31 CN disclosed
CN-113820920-A Photosensitive resin composition, method for producing cured relief pattern, and semiconductor device 旭化成株式会社 2021-12-21 CN disclosed
EP-0273980-A1 CAN WITH AN EASILY OPENABLE LID AND A PROCESS FOR PRODUCING THE SAME TOYO SEIKAN KAISHA, LTD. (JP) 1988-07-13 EP disclosed
US-4701354-A VAPOR DEPOSITION OF AN HYDROXYMETHYL SUBSTITUTED PHENOL TOYO SEIKAN KAISHA, LTD. (JP) 1987-10-20 US disclosed
EP-0104643-A2 5-Membered cyclic phosphonates and compositions thereof The B.F. GOODRICH Company (US) 1984-04-04 EP disclosed
US-4259464-A CURING AGENTS, EMULSIFIERS, DEMULSIFIERS, DETERGENTS, BACTERICIDES PETROLITE CORPORATION (US) 1981-03-31 US disclosed
US-4248976-A COMPRISING A PHOSPHORUS COMPOUND AND AN AROMATIC COMPOUND CIBA-GEIGY AG (CH) 1981-02-03 US disclosed
US-4219570-A Insect repellents and a method of repelling insects AJINOMOTO COMPANY, INCORPORATED (JP) 1980-08-26 US disclosed
US-4172858-A Flame-resistant polymer compositions CIBA-GEIGY AG (CH) 1979-10-30 US disclosed
US-4098717-A WATER IN OIL EMULSIONS PETROLITE CORPORATION (US) 1978-07-04 US disclosed
US-4032514-A THIOALKYLATED OR AMINOALKYLATED, INFUSIBLE PETROLITE CORPORATION (US) 1977-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548850-B2 Development of a cofilin inhibitor for the treatment of hemorrhagic brain injury-induced neuroinflammation CFL1, NFKBIA, LIMA1 KLF10 1817/4885CYP2D6 4863/4885ALDH1A1 4352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.