Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3849915 | 0.88 | MAPT (0.49) | ALDH1A1TSHRDRD2DRD3HTR1A | |
| SCHEMBL4523959 | 0.88 | GPR119 (0.56) | ALDH1A1TSHRDRD2DRD3HTR1A | |
| SCHEMBL2723301 | 0.83 | MAPT (0.58) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL4755524 | 0.81 | DRD2 (0.50) | DRD2DRD3HTR2A | |
| SCHEMBL4503964 | 0.81 | CHRNA10 (0.51) | ALDH1A1DRD2DRD3HTR1A | |
| SCHEMBL4701304 | 0.80 | DRD2 (0.49) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL8205972 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TSHRDRD2TDP1MEN1 | |
| SCHEMBL24754432 | 0.79 | HTT (0.50) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL4514129 | 0.79 | DRD2 (0.58) | ALDH1A1DRD2DRD3HTR1AMEN1 | |
| SCHEMBL22015905 | 0.78 | HPGD (0.65) | ALDH1A1TSHRTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | GPR119, GCGR, GPBAR1 | ALDH1A1 1188/4885TSHR 209/4885DRD2 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.