Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | USP2 | O75604 | 7/20 | 0.43 |
| ▸ | CASP1 | P29466 | 6/20 | 0.43 |
| ▸ | CASP7 | P55210 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526092 | 0.89 | YTHDC1 (0.45) | TSHRYTHDC1HTTALDH1A1CYP1A2 | |
| SCHEMBL4531049 | 0.88 | HPGD (0.46) | TSHRYTHDC1LMNAHTTXBP1 | |
| SCHEMBL4521275 | 0.87 | ALDH1A3 (0.44) | YTHDC1NPSR1ALDH1A1THRB | |
| SCHEMBL4505408 | 0.87 | YTHDC1 (0.46) | HSD17B10TSHRYTHDC1ALDH1A1CYP1A2 | |
| SCHEMBL4520999 | 0.86 | NPC1 (0.44) | YTHDC1ALDH1A1HIF1ARXFP1ADORA2A | |
| SCHEMBL4521578 | 0.85 | TP53 (0.42) | YTHDC1TP53MEN1KMT2A | |
| SCHEMBL4517002 | 0.84 | YTHDC1 (0.48) | YTHDC1RXFP1 | |
| SCHEMBL4509737 | 0.83 | CNR1 (0.38) | HSD17B10TSHRYTHDC1LMNAHTT | |
| SCHEMBL4520072 | 0.82 | MAT2A (0.38) | TSHRYTHDC1LMNAHTTXBP1 | |
| SCHEMBL4525433 | 0.81 | POLB (0.37) | TSHRYTHDC1LMNAHTTXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298856-A1 | 2,3 Substituted fused bicyclic pyrimidin-4(3H)-ones modulating the function of the vanilliod-1receptor (VR1) | BROWN REBECCA ELIZABETH | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298856-A1 | 2,3 Substituted fused bicyclic pyrimidin-4(3H)-ones modulating the function of the vanilliod-1receptor (VR1) | TRPV1, TRPV2, TRPV4 | HSD17B10 3289/4885TSHR 915/4885YTHDC1 4699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.