Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | CASP3 | P42574 | 4/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512031 | 0.87 | ALOX5 (0.46) | ALOX5AGPAT2HPGDKDM4ERAB9A | |
| SCHEMBL4544546 | 0.80 | KDM4E (0.44) | ALOX5AGPAT2HPGDKDM4ERAB9A | |
| SCHEMBL4502713 | 0.79 | ALOX5 (0.49) | ALOX5AGPAT2HPGDKDM4ERAB9A | |
| SCHEMBL3136330 | 0.75 | KDM4E (0.50) | ALOX5AGPAT2HPGDKDM4ERAB9A | |
| SCHEMBL4500826 | 0.74 | KDM4E (0.54) | ALOX5AGPAT2HPGDKDM4ERAB9A | |
| SCHEMBL3136773 | 0.74 | KDM4E (0.54) | HPGDKDM4ERAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3142243 | 0.72 | KDM4E (0.55) | ALOX5HPGDKDM4ERAB9AALDH1A1 | |
| SCHEMBL3137262 | 0.71 | RAB9A (0.46) | ALOX5AGPAT2HPGDKDM4ERAB9A | |
| SCHEMBL3137253 | 0.71 | RAB9A (0.46) | ALOX5AGPAT2HPGDKDM4ERAB9A | |
| SCHEMBL22103734 | 0.70 | NPC1 (0.81) | ALOX5HPGDKDM4ERAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-10-15 | — | — | US | disclosed |
| EP-1933834-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007042816-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | ALOX5 504/4885AGPAT2 4533/4885HPGD 411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.