SCHEMBL4513203

SCHEMBL4513203

Nc1ccc([Si](O)(O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 8/20 0.45
CYP3A4 P08684 5/20 0.45
ALOX15 P16050 2/20 0.45
CA3 P07451 1/20 0.45
THRB P10828 1/20 0.45
CA6 P23280 1/20 0.45
CASP1 P29466 1/20 0.45
HIF1A Q16665 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CA14 Q9ULX7 1/20 0.45
TDP1 Q9NUW8 5/20 0.42
TP53 P04637 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 2/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
TSHR P16473 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4535157 0.92 CYP3A4 (0.58) MAPTMEN1KMT2AALDH1A1CYP3A4
SCHEMBL272403 0.83 ESR1 (0.30)
SCHEMBL4511521 0.81 MAPT (0.50) MAPTMEN1KMT2AALDH1A1CYP3A4
SCHEMBL4516363 0.77 MEN1 (0.44) MAPTMEN1KMT2AALDH1A1CYP3A4
SCHEMBL9326306 0.77 MEN1 (0.44) MAPTMEN1KMT2AALDH1A1CYP3A4
SCHEMBL6433749 0.73 ESR1 (0.39) MAPTMEN1KMT2AALDH1A1CYP3A4
SCHEMBL2119390 0.73 MEN1 (0.57) MAPTMEN1KMT2AALDH1A1CYP3A4
SCHEMBL15684574 0.71 ALOX15 (0.53) MAPTMEN1KMT2AALDH1A1CYP3A4
SCHEMBL4527473 0.71 ALDH1A1 (0.52) MAPTMEN1KMT2AALDH1A1CYP3A4
SCHEMBL320609 0.71 MEN1 (1.00) MAPTMEN1KMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210017420-A1 STRUCTURE BODY, SENSOR, AND METHOD FOR PRODUCING STRUCTURE BODY DENSO CORPORATION (JP) 2021-01-21 US claimed
WO-2019193943-A1 STRUCTURE BODY, SENSOR, AND STRUCTURE BODY PRODUCTION METHOD 株式会社デンソー 2019-10-10 WO claimed
JP-61259788-A None JP disclosed
US-11485877-B2 Structure body, sensor, and method for producing structure body DENSO CORPORATION (JP) 2022-11-01 US disclosed
US-20210017420-A1 STRUCTURE BODY, SENSOR, AND METHOD FOR PRODUCING STRUCTURE BODY DENSO CORPORATION (JP) 2021-01-21 US disclosed
US-20210017420-A1 STRUCTURE BODY, SENSOR, AND METHOD FOR PRODUCING STRUCTURE BODY DENSO CORPORATION (JP) 2021-01-21 US disclosed
WO-2019193943-A1 STRUCTURE BODY, SENSOR, AND STRUCTURE BODY PRODUCTION METHOD 株式会社デンソー 2019-10-10 WO disclosed
WO-2019193943-A1 STRUCTURE BODY, SENSOR, AND STRUCTURE BODY PRODUCTION METHOD 株式会社デンソー 2019-10-10 WO disclosed
US-8709677-B2 Proton conducting electrolytes with cross-linked copolymer additives for use in fuel cells DAIMLER AG (DE) 2014-04-29 US disclosed
US-8710108-B2 Proton conducting electrolytes with cross-linked copolymer additives for use in fuel cells DAIMLER AG (DE) 2014-04-29 US disclosed
US-8710108-B2 Proton conducting electrolytes with cross-linked copolymer additives for use in fuel cells DAIMLER AG (DE) 2014-04-29 US disclosed
US-8709677-B2 Proton conducting electrolytes with cross-linked copolymer additives for use in fuel cells DAIMLER AG (DE) 2014-04-29 US disclosed
US-20120225372-A1 PROTON CONDUCTING ELECTROLYTES WITH CROSS-LINKED COPOLYMER ADDITIVES FOR USE IN FUEL CELLS FORD MOTOR COMPANY (US) 2012-09-06 US disclosed
US-20120225958-A1 PROTON CONDUCTING ELECTROLYTES WITH CROSS-LINKED COPOLYMER ADDITIVES FOR USE IN FUEL CELLS FORD MOTOR COMPANY (US) 2012-09-06 US disclosed
US-7507480-B2 Corrosion-resistant metal surfaces BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2009-03-24 US disclosed
US-20060269760-A1 Corrosion-resistant metal surfaces ENERGY, UNITED STATES DEPARTMENT OF 2006-11-30 US disclosed
JP-S61259788-A METHOD OF COATING THREE-DIMENSIONAL RETICULATED CURABLE PAINT MITSUBISHI HEAVY IND LTD 1986-11-18 JP disclosed
US-4246145-A CONTAINING AN ADHESIVE AND AN ORGANOSILANETRIOL SAINT-GOBAIN INDUSTRIES (FR) 1981-01-20 US disclosed
US-4244844-A COATING OF POLYAZAMIDE CHAIN OF AN ORGANOSILANE WITH STARCHES AND LUBRICANTS SAINT-GOBAIN INDUSTRIES (FR) 1981-01-13 US disclosed