SCHEMBL4514221

SCHEMBL4514221

O=P(c1ccccc1)(c1ccc(OC(F)=C(F)F)cc1)c1ccc(OC(F)=C(F)F)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.40
CA2 P00918 3/20 0.38
CA4 P22748 3/20 0.38
CA5A P35218 3/20 0.38
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ESR1 P03372 2/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
CA5B Q9Y2D0 2/20 0.36
MAPT P10636 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HSP90AA1 P07900 1/20 0.35
GAA P10253 1/20 0.35
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4518638 0.93 MEN1 (0.32) MEN1KMT2A
SCHEMBL13422208 0.79 KMT2A (0.43) MEN1KMT2ALMNACA2TDP1
SCHEMBL2330129 0.78 LTA4H (0.41) CA4CA5ATDP1L3MBTL1CA5B
SCHEMBL4530562 0.76 RAB9A (0.35) MEN1KMT2ALMNATDP1ESR1
SCHEMBL29177739 0.74 LTA4H (0.50) MEN1KMT2ALMNACA2CA4
SCHEMBL12833375 0.74 KIF11 (0.39) MEN1KMT2ALMNAESR1GAA
SCHEMBL8934991 0.74 KIF11 (0.39) MEN1KMT2ALMNAESR1GAA
SCHEMBL1505815 0.74 KIF11 (0.39) MEN1KMT2ALMNAESR1GAA
SCHEMBL6635153 0.73 NSD2 (0.39) MEN1KMT2ACA2TDP1L3MBTL1
SCHEMBL5439069 0.73 LMNA (0.60) MEN1KMT2ALMNACA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7457508-B2 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2008-11-25 US claimed
US-7570864-B2 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same ALCATEL-LUCENT USA INC. (US) 2009-08-04 US disclosed
US-20090034930-A1 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2009-02-05 US disclosed
US-7457508-B2 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2008-11-25 US disclosed
US-20070217755-A1 Polymeric compositions comprising quantum dots,optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2007-09-20 US disclosed
WO-2007052954-A1 BLOCK COPOLYMERS CONTAINING PERFLUOROCYCLOBUTANE RINGS AND ELECTROLYTE MEMBRANES USING THE SAME LG CHEM, LTD. (KR) 2007-05-10 WO disclosed
US-7197226-B2 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2007-03-27 US disclosed
US-20060208223-A1 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2006-09-21 US disclosed
US-7065285-B2 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2006-06-20 US disclosed
US-20050117868-A1 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same BARINGS FINANCE LLC, AS COLLATERAL AGENT 2005-06-02 US disclosed