Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.49 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.48 |
| ▸ | MEP1A | Q16819 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4490305 | 0.85 | LOXL2 (0.52) | SMN1; SMN2NPC1HPGDRAB9AMRGPRX4 | |
| SCHEMBL10766037 | 0.84 | MEN1 (0.58) | MEN1KMT2AHPGDLMNA | |
| SCHEMBL10433003 | 0.80 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL168738 | 0.77 | FOLH1 (0.59) | MEN1KMT2ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL29630981 | 0.77 | FOLH1 (0.59) | MEN1KMT2ASMN1; SMN2TP53NFKB1 | |
| Hydrochloric Acid SCHEMBL15067497 | 0.76 | FOLH1 (0.58) | MEN1KMT2ASMN1; SMN2TP53NFKB1 | |
| Hydrochloric Acid SCHEMBL29690742 | 0.76 | FOLH1 (0.58) | MEN1KMT2ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL2117243 | 0.76 | SMN1; SMN2 (0.71) | MEN1KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL4836068 | 0.74 | MEN1 (0.63) | MEN1KMT2ANPC1RAB9AMEP1B | |
| SCHEMBL11811255 | 0.74 | MEP1B (0.72) | MEN1KMT2AMEP1BMEP1AFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | MEN1 4180/4885KMT2A 1109/4885SMN1; SMN2 2075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.