Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | TERT | O14746 | 3/20 | 0.37 |
| ▸ | CYCS | P99999 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513613 | 0.88 | ENPP2 (0.50) | ENPP2TOP1TERTCYCS | |
| SCHEMBL4510674 | 0.84 | STAT3 (0.46) | ENPP2 | |
| SCHEMBL3289548 | 0.79 | NUDT1 (0.45) | ENPP2TOP1TERTCYCS | |
| SCHEMBL1613981 | 0.75 | ENPP2 (0.55) | ENPP2TOP1TERTCYCS | |
| SCHEMBL30925048 | 0.74 | ENPP2 (0.54) | ENPP2TOP1TERTCYCS | |
| SCHEMBL5178493 | 0.74 | ENPP2 (0.47) | ENPP2TOP1TERTCYCS | |
| SCHEMBL1537566 | 0.74 | ENPP2 (0.57) | ENPP2TOP1TERTCYCS | |
| SCHEMBL1537557 | 0.74 | ENPP2 (0.47) | ENPP2TOP1TERTCYCS | |
| SCHEMBL9290728 | 0.74 | ENPP2 (0.47) | ENPP2TOP1TERTCYCS | |
| SCHEMBL1537544 | 0.74 | ENPP2 (0.54) | ENPP2TOP1TERTCYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592404-B2 | Derivatives of porphyrin, particularly chlorins and/or bacteriochlorins, and uses thereof in photodynamic therapy | UNIVERSIDADE DE COIMBRA (PT) | 2013-11-26 | — | — | US | disclosed |
| US-20090149525-A1 | NOVEL DERIVATIVES OF PORPHYRIN, PARTICULARLY CHLORINS AND/OR BACTERIOCHLORINS, AND USES THEREOF IN PHOTODYNAMIC THERAPY | UNIVERSIDADE DE COIMBRA (PT) | 2009-06-11 | — | — | US | disclosed |
| EP-1811994-B1 | NOVEL DERIVATIVES OF PORPHYRIN, PARTICULARLY CHLORINS AND BACTERIOCHLORINS, AND USES THEREOF IN PHOTODYNAMIC THERAPY | UNIV DE COIMBRA (PT) | 2008-06-25 | — | — | EP | disclosed |
| EP-1811994-A1 | NOVEL DERIVATIVES OF PORPHYRIN, PARTICULARLY CHLORINS AND/OR BACTERIOCHLORINS, AND USES THEREOF IN PHOTODYNAMIC THERAPY | Universidade de Coimbra (PT) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006053707-A1 | NOVEL DERIVATIVES OF PORPHYRIN, PARTICULARLY CHLORINS AND/OR BACTERIOCHLORINS, AND USES THEREOF IN PHOTODYNAMIC THERAPY | UNIVERSIDADE DE COIMBRA (PT) | 2006-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149525-A1 | NOVEL DERIVATIVES OF PORPHYRIN, PARTICULARLY CHLORINS AND/OR BACTERIOCHLORINS, AND USES THEREOF IN PHOTODYNAMIC THERAPY | PPOX, PYCR1, XPA | ENPP2 2193/4885TOP1 1685/4885TERT 2777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.