Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4520656 | 0.84 | HSD11B1 (0.40) | HSD11B1LMNAOPRL1OPRM1CNR1 | |
| SCHEMBL4504673 | 0.78 | ALDH1A1 (0.34) | HSD11B1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL4518734 | 0.71 | SIGMAR1 (0.45) | — | |
| SCHEMBL4504999 | 0.70 | HSD11B1 (0.39) | HSD11B1MAPTOPRL1OPRM1OPRD1 | |
| SCHEMBL5541309 | 0.69 | HSD11B1 (0.49) | HSD11B1LMNATSHRNPSR1MEN1 | |
| SCHEMBL4509861 | 0.67 | HSD11B1 (0.39) | HSD11B1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL4523661 | 0.65 | LMNA (0.39) | MAPTLMNATSHRNPSR1MEN1 | |
| SCHEMBL3554597 | 0.65 | HSD11B1 (0.67) | HSD11B1MAPTLMNATSHRMEN1 | |
| SCHEMBL4509824 | 0.65 | HSD11B1 (0.46) | HSD11B1LMNAOPRK1 | |
| SCHEMBL4515325 | 0.65 | HSD11B1 (0.49) | HSD11B1MAPTLMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | HSD11B1 1/4885MAPT 4692/4885LMNA 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.