SCHEMBL308354

SCHEMBL308354

C=Cc1ccccc1C.ClCC=Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 1/20 0.38
APOBEC3A P31941 1/20 0.38
RAB9A P51151 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
HTR2A P28223 3/20 0.38
TSHR P16473 2/20 0.36
IDO1 P14902 2/20 0.36
PAM P19021 1/20 0.36
TTR P02766 1/20 0.35
ALOX5 P09917 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
PTGER4 P35408 1/20 0.35
PTGER3 P43115 1/20 0.35
PTGER2 P43116 1/20 0.35
TRPA1 O75762 1/20 0.34
NFE2L2 Q16236 1/20 0.34
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451576 0.88 ALDH1A1 (0.43) ALDH1A1RAB9AHTR2ATSHRIDO1
SCHEMBL7643574 0.85 ALDH1A1 (0.39) ALDH1A1KDM4EAPOBEC3ARAB9AAPOBEC3G
Styrene SCHEMBL9488136 0.85 ALDH1A1 (0.50) ALDH1A1RAB9AHTR2ATSHRIDO1
SCHEMBL15421494 0.84 HTR2A (0.38) ALDH1A1HTR2ATSHRIDO1PAM
SCHEMBL6543156 0.84 ALDH1A1 (0.38) ALDH1A1KDM4EAPOBEC3ARAB9AAPOBEC3G
SCHEMBL28469201 0.83 SIGMAR1 (0.40) ALDH1A1KDM4EAPOBEC3ARAB9AAPOBEC3G
SCHEMBL7049969 0.81 RAB9A (0.41) ALDH1A1KDM4EAPOBEC3ARAB9AAPOBEC3G
Styrene SCHEMBL1507248 0.81 ALDH1A1 (0.58) ALDH1A1RAB9AHTR2ATSHRIDO1
SCHEMBL2376149 0.80 SIGMAR1 (0.38) ALDH1A1KDM4EAPOBEC3ARAB9AAPOBEC3G
SCHEMBL2336589 0.80 KDM4E (0.42) ALDH1A1KDM4EAPOBEC3ARAB9AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1248679-B1 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, OR PARTICLE AND PROTEIN COMPLEXES, REAGENT AND USES BIO MERIEUX (FR) 2005-03-09 EP claimed
US-20030175691-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIO MERIEUX (FR) 2003-09-18 US claimed
EP-1248679-A2 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, OR PARTICLE AND PROTEIN COMPLEXES, REAGENT AND USES BIO MERIEUX (FR) 2002-10-16 EP claimed
WO-2001052612-A2 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, AND RESULTING COMPLEXES OF PARTICLES AND PROTEINS BIO MERIEUX (FR) 2001-07-26 WO claimed
WO-2001052979-A1 METHOD FOR PREPARING STABLE AND FUNCTIONALISED COLLOIDAL PARTICLES AND RESULTING PARTICULATE REAGENT BIO MERIEUX (FR) 2001-07-26 WO claimed
US-8093026-B2 Method for transporting or storing a protein, a virus, a prokaryotic cell, or an eukaryotic cell BIOMERIEUX (FR) 2012-01-10 US disclosed
US-20100209987-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2010-08-19 US disclosed
US-7700744-B2 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2010-04-20 US disclosed
US-7060804-B2 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2006-06-13 US disclosed
US-20060105326-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2006-05-18 US disclosed
EP-1248679-B1 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, OR PARTICLE AND PROTEIN COMPLEXES, REAGENT AND USES BIO MERIEUX (FR) 2005-03-09 EP disclosed
US-20030175691-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIO MERIEUX (FR) 2003-09-18 US disclosed
EP-1248679-A2 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, OR PARTICLE AND PROTEIN COMPLEXES, REAGENT AND USES BIO MERIEUX (FR) 2002-10-16 EP disclosed
WO-2002046759-A1 DEVICE FOR CAPTURING A TARGET MOLECULE BIO MERIEUX (FR) 2002-06-13 WO disclosed
WO-2001052979-A1 METHOD FOR PREPARING STABLE AND FUNCTIONALISED COLLOIDAL PARTICLES AND RESULTING PARTICULATE REAGENT BIO MERIEUX (FR) 2001-07-26 WO disclosed
WO-2001052612-A2 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, AND RESULTING COMPLEXES OF PARTICLES AND PROTEINS BIO MERIEUX (FR) 2001-07-26 WO disclosed