Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | IDE | P14735 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515995 | 0.90 | ALDH1A1 (0.36) | P2RX7ALDH1A1IDELMNASMN1; SMN2 | |
| SCHEMBL5543748 | 0.86 | S1PR1 (0.34) | P2RX7ALDH1A1IDELMNA | |
| SCHEMBL4504312 | 0.85 | ALDH1A1 (0.38) | P2RX7ALDH1A1IDEKMT2A | |
| SCHEMBL14365303 | 0.83 | P2RX7 (0.37) | P2RX7ALDH1A1IDELMNASMN1; SMN2 | |
| SCHEMBL4520440 | 0.82 | IDE (0.35) | P2RX7ALDH1A1IDELMNASMN1; SMN2 | |
| SCHEMBL4514407 | 0.80 | KDM1A (0.35) | ALDH1A1IDELMNASMN1; SMN2 | |
| SCHEMBL5127854 | 0.79 | P2RX7 (0.38) | P2RX7ALDH1A1IDELMNASMN1; SMN2 | |
| SCHEMBL5132089 | 0.77 | ALDH1A1 (0.37) | P2RX7ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4514378 | 0.76 | CYP3A4 (0.36) | ALDH1A1IDE | |
| SCHEMBL4506472 | 0.76 | ALDH1A1 (0.48) | P2RX7ALDH1A1IDESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1864971-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2007-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | P2RX7 3946/4885ALDH1A1 51/4885IDE 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.