Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 7/20 | 0.41 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | PHGDH | O43175 | 4/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4518310 | 0.89 | PHGDH (0.40) | EPHA2GRM5PHGDHRBP4KDR | |
| Trifluoroacetic Acid SCHEMBL4504667 | 0.89 | EPHA2 (0.41) | EPHA2GRM5PHGDHRBP4DRD4 | |
| Trifluoroacetic Acid SCHEMBL4495237 | 0.88 | TRPV1 (0.40) | GRM5PHGDHDRD4TRPV1 | |
| Trifluoroacetic Acid SCHEMBL4506318 | 0.88 | PHGDH (0.39) | GRM5PHGDHDRD4TRPV1 | |
| Trifluoroacetic Acid SCHEMBL4505237 | 0.88 | TRPV1 (0.39) | EPHA2GRM5PHGDHRBP4TRPV1 | |
| Trifluoroacetic Acid SCHEMBL4510447 | 0.88 | RBP4 (0.46) | PHGDHRBP4TRPV1 | |
| Trifluoroacetic Acid SCHEMBL4498992 | 0.87 | PHGDH (0.40) | EPHA2PHGDHDRD4KDM4EMEN1 | |
| Trifluoroacetic Acid SCHEMBL4515416 | 0.87 | GRM5 (0.43) | GRM5PHGDHDRD4TRPV1 | |
| Trifluoroacetic Acid SCHEMBL4516194 | 0.87 | GRM5 (0.40) | EPHA2GRM5PHGDHRBP4DRD4 | |
| Trifluoroacetic Acid SCHEMBL4501514 | 0.86 | PDK1 (0.47) | GRM5PHGDHDRD4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | EPHA2 4379/4885GRM5 4026/4885PHGDH 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.