SCHEMBL451641

SCHEMBL451641

CCCCC(CC)Cc1cccc(OP(=O)(Oc2cccc(CC(CC)CCCC)c2CC(CC)CCCC)Oc2cccc(CC(CC)CCCC)c2CC(CC)CCCC)c1CC(CC)CCCC

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TSHR P16473 3/20 0.39
GLA P06280 1/20 0.39
HTT P42858 1/20 0.39
ALDH1A1 P00352 4/20 0.37
CA2 P00918 1/20 0.37
LMNA P02545 2/20 0.34
PTGES O14684 1/20 0.34
ALOX5 P09917 1/20 0.34
PPARG P37231 1/20 0.34
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451642 0.90 TSHR (0.39) CYP3A4L3MBTL1TSHRGLAHTT
SCHEMBL29536728 0.90 TSHR (0.39) CYP3A4L3MBTL1TSHRGLAHTT
SCHEMBL5936011 0.88 CYP3A4 (0.44) CYP3A4L3MBTL1TSHRGLAHTT
SCHEMBL17491629 0.86 TSHR (0.36) CYP3A4L3MBTL1TSHRGLAHTT
SCHEMBL17491585 0.85 TSHR (0.38) CYP3A4L3MBTL1TSHRGLAHTT
SCHEMBL17491588 0.84 TSHR (0.35) CYP3A4L3MBTL1TSHRGLAHTT
SCHEMBL17491636 0.84 P2RY10 (0.38) CYP3A4L3MBTL1TSHRALDH1A1CA2
SCHEMBL29178174 0.82 L3MBTL1 (0.39) CYP3A4L3MBTL1TSHRGLAHTT
SCHEMBL22289762 0.81 ALDH1A1 (0.41) CYP3A4L3MBTL1TSHRGLAHTT
SCHEMBL11395011 0.81 ALDH1A1 (0.36) CYP3A4L3MBTL1TSHRGLAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 666 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070149661-A1 POLYCARBONATE COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME CITIBANK, N.A., AS COLLATERAL AGENT 2007-06-28 US claimed
US-20010049025-A1 Multilayer films having flame retardant layers 3M INNOVATIVE PROPERTIES COMPANY 2001-12-06 US claimed
US-12570848-B2 Scratch-resistant high impact strength PMMA compositions SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-03-10 US disclosed
US-20260002025-A1 POLYCARBONATE COMPOSITION, ARTICLES FORMED THEREFORE, AND METHODS FOR THE MANUFACTURE THEREOF SHPP GLOBAL TECH BV (NL) 2026-01-01 US disclosed
US-12473734-B2 Synthetic flashing material REDEAHOLD APELDOORN B.V. (NL) 2025-11-18 US disclosed
US-12441868-B2 Polyolefin formulation Dow Global Technlogies LLC (US) 2025-10-14 US disclosed
EP-4615898-A1 HIGH RESILIENT THERMOPLASTIC POLYURETHANES AND USES THEREOF Lubrizol Advanced Materials, Inc. (US) 2025-09-17 EP disclosed
US-12403437-B2 Method for producing nanodiamonds doped with group 14 element, and method for purifying same DAICEL CORPORATION (JP) 2025-09-02 US disclosed
US-20250257212-A1 POLYCARBONATE COMPOSITION, ARTICLES FORMED THEREFROM, AND METHODS FOR THE MANUFACTURE THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-08-14 US disclosed
US-12351463-B2 Heteroatom-doped nanodiamond DAICEL CORPORATION (JP) 2025-07-08 US disclosed
EP-4172269-B1 THERMOPLASTIC COMPOSITIONS WITH IMPROVED HYDROLYTIC AND HEAT STABILITY SHPP GLOBAL TECH BV (NL) 2025-05-28 EP disclosed
US-4086212-A ESTERIFICATION OR TRANSESTERIFICATION BAYER AKTIENGESELLSCHAFT (DT) 1978-04-25 US disclosed
US-4020124-A Blends of a polyphenylene ether resin, alkenyl aromatic resins modified with EPDM rubber and graft polymerized high rubber content polymers GENERAL ELECTRIC COMPANY (US) 1977-04-26 US disclosed
US-4013613-A INCLUDING ADDITION POLYMER GENERAL ELECTRIC COMPANY (US) 1977-03-22 US disclosed
US-4002581-A MOLDINGS GENERAL ELECTRIC COMPANY (US) 1977-01-11 US disclosed
US-3981841-A MOLDING MATERIALS, IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1976-09-21 US disclosed
US-3974235-A Blends of a polyphenylene ether resin, alkenyl aromatic resins modified with EPDM rubber and flame retardant GENERAL ELECTRIC COMPANY (US) 1976-08-10 US disclosed
US-3959211-A ETHYLENE-ALPHA-OLEFIN-DIENE GENERAL ELECTRIC COMPANY (US) 1976-05-25 US disclosed
US-3953394-A POLYETHYLENE TEREPHTHALATE-POLYBUTYLENE TEREPHTHALATE BLENDS GENERAL ELECTRIC COMPANY (US) 1976-04-27 US disclosed
US-3943191-A MOLDING GENERAL ELECTRIC COMPANY (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260002025-A1 POLYCARBONATE COMPOSITION, ARTICLES FORMED THEREFORE, AND METHODS FOR THE MANUFACTURE THEREOF LCP1, COL2A1, SHBG CYP3A4 1372/4885L3MBTL1 3176/4885TSHR 2616/4885
US-12570848-B2 Scratch-resistant high impact strength PMMA compositions PCNA, COL2A1, COL1A1 CYP3A4 3771/4885L3MBTL1 1383/4885TSHR 4730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.