SCHEMBL451746

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL449936	0.89	ALDH1A1 (0.36)	AURKAEGFRKDRALDH1A1HPGD
	SCHEMBL30795166	0.81	CYP2C9 (0.39)	LMNACYP1A2CYP2C9CYP2C19TRPV1
	SCHEMBL448838	0.81	CYP2C9 (0.39)	LMNACYP1A2CYP2C9CYP2C19TRPV1
	SCHEMBL438018	0.78	TOP2A (0.38)	EGFRMETKDRALDH1A1MEN1
	SCHEMBL30795090	0.77	LMNA (0.40)	LMNACYP1A2CYP2C9CYP2C19GAA
	SCHEMBL448018	0.77	LMNA (0.40)	LMNACYP1A2CYP2C9CYP2C19GAA
	SCHEMBL448977	0.74	CYP2C19 (0.46)	LMNACYP2C19GAAALDH1A1MEN1
	SCHEMBL449608	0.69	GSTO1 (0.58)	LMNAGAACDK2ALDH1A1MEN1
	SCHEMBL448080	0.69	CAMK2A (0.41)	LMNACYP2C9GAAALDH1A1KMT2A
	SCHEMBL30794731	0.69	CAMK2A (0.41)	LMNACYP2C9GAAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.