Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51319 | 0.86 | TRPA1 (0.64) | TRPA1HSPA5HSD17B10ALOX15BACE1 | |
| SCHEMBL28298946 | 0.85 | ESR1 (0.63) | KEAP1HSPA5HSD17B10ALOX15MEN1 | |
| SCHEMBL11415887 | 0.84 | CNR1 (0.52) | ALOX15BACE1HPGDHTTCNR2 | |
| SCHEMBL4517872 | 0.84 | MEN1 (0.61) | TRPA1KEAP1HSD17B10ALOX15BACE1 | |
| SCHEMBL3638974 | 0.83 | GABRA1 (0.63) | TRPA1KEAP1HSPA5HSD17B10ALOX15 | |
| SCHEMBL5677011 | 0.82 | CNR1 (0.56) | HSD17B10CYP3A4HIF1ASHBGESR1 | |
| SCHEMBL21307639 | 0.81 | TRPA1 (0.53) | TRPA1KEAP1HSD17B10ALOX15BACE1 | |
| SCHEMBL7759834 | 0.81 | KEAP1 (0.48) | KEAP1HSPA5HSD17B10ALOX15MEN1 | |
| SCHEMBL1409748 | 0.81 | AMY1A (0.65) | TRPA1HSPA5HSD17B10ALOX15MEN1 | |
| SCHEMBL21307638 | 0.80 | GABRA1 (0.57) | TRPA1HSPA5HSD17B10ALOX15BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162518-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2009009293-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |
| US-20090011961-A1 | Lubricant compositions stabilized with styrenated phenolic antioxidant | CROMPTON HOLDING CORPORATION | 2009-01-08 | — | — | US | disclosed |