Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.49 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224497 | 0.88 | SMN1; SMN2 (0.46) | KMODHODHSMN1; SMN2NPC1MAPT | |
| SCHEMBL4514183 | 0.87 | DHODH (0.46) | KMODHODHSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL4520576 | 0.87 | DHODH (0.48) | DHODHSMN1; SMN2MAP4K4LMNA | |
| SCHEMBL9155779 | 0.83 | KMO (0.46) | KMODHODHANO1SMN1; SMN2NPC1 | |
| SCHEMBL9157192 | 0.83 | KMO (0.46) | KMODHODHANO1SMN1; SMN2NPC1 | |
| SCHEMBL27463643 | 0.83 | LOXL2 (0.43) | DHODHSMN1; SMN2LMNA | |
| SCHEMBL6772451 | 0.77 | LMNA (0.42) | DHODHSMN1; SMN2ALDH1A1TDP1MAP4K4 | |
| SCHEMBL4523605 | 0.75 | KMO (0.51) | KMODHODHMAP4K4FYN | |
| SCHEMBL4520735 | 0.75 | NOTUM (0.41) | KMOSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL28143127 | 0.75 | CDC7 (0.46) | DHODHSMN1; SMN2CYP3A4LMNAFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625887-B2 | Receptor agonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-01 | — | — | US | disclosed |
| US-20060199795-A1 | Receptor agonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-09-07 | — | — | US | disclosed |
| EP-1591120-A1 | RECEPTOR AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2005-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199795-A1 | Receptor agonists | GPBAR1, GPR35, GPR55 | KMO 1310/4885DHODH 2221/4885ANO1 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.