Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509555 | 0.82 | SCN9A (0.54) | SCN9AHTR6BCHEKMT2AMEN1 | |
| SCHEMBL4505528 | 0.80 | ALDH1A1 (0.52) | LOXL2SCDSMN1; SMN2CCR3 | |
| SCHEMBL4499579 | 0.77 | RBP4 (0.53) | SCN9AHTR6BCHERBP4ALOX5AP | |
| SCHEMBL4496434 | 0.74 | LOXL2 (0.46) | LOXL2SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4504665 | 0.74 | SMN1; SMN2 (0.54) | SCDSMN1; SMN2MGLLCCR3 | |
| SCHEMBL4506697 | 0.73 | HTR6 (0.54) | SCN9AHTR6SMN1; SMN2BCHEKMT2A | |
| SCHEMBL4518274 | 0.73 | KMT2A (0.52) | LOXL2SMN1; SMN2KMT2AMEN1RBP4 | |
| SCHEMBL27157955 | 0.73 | SCN9A (0.55) | SCN9AHTR6BCHERBP4ALOX5AP | |
| SCHEMBL30785411 | 0.73 | POLB (0.52) | SCN9AHTR6BCHEALOX5APFEN1 | |
| SCHEMBL27158239 | 0.73 | POLB (0.52) | SCN9AHTR6BCHEALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | LOXL2 2411/4885SCD 1/4885SCN9A 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.