Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4518901 | 1.00 | HPGDS (0.50) | HPGDSL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL2308432 | 0.95 | HPGDS (0.49) | HPGDSL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL2308438 | 0.95 | HPGDS (0.49) | HPGDSL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL13779739 | 0.89 | HPGDS (0.43) | HPGDSL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13209703 | 0.89 | HPGDS (0.43) | HPGDSL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2636782 | 0.88 | CHRNB2 (0.43) | HPGDSNPC1RAB9ASMN1; SMN2AR | |
| SCHEMBL2636780 | 0.88 | CHRNB2 (0.43) | HPGDSNPC1RAB9ASMN1; SMN2AR | |
| SCHEMBL15453507 | 0.85 | SMN1; SMN2 (0.49) | L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL2308428 | 0.84 | BAZ2A (0.46) | HPGDSNPC1RAB9ASMN1; SMN2AR | |
| SCHEMBL2308422 | 0.84 | BAZ2A (0.46) | HPGDSNPC1RAB9ASMN1; SMN2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478359-B | Carbamate TRPV1 antagonism/FAAH inhibition double-target drug, and preparation method and application thereof | 河南大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-111423432-B | (S) -4/5-phenyl-2- (pyrrolidine-2-yl) thiazole TRPV1 antagonist and preparation and application thereof | 河南大学 | 2023-01-24 | — | — | CN | disclosed |
| CN-114478359-A | Carbamate TRPV1 antagonistic/FAAH inhibition double-target medicine and preparation method and application thereof | 河南大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-111423432-A | (S) -4/5-phenyl-2- (pyrrolidine-2-yl) thiazole TRPV1 antagonist and preparation and application thereof | 河南大学 | 2020-07-17 | — | — | CN | disclosed |
| US-20090318445-A1 | PDF INHIBITORS | NORVARTIS AG (CH) | 2009-12-24 | — | — | US | disclosed |
| EP-1973898-A1 | PDF INHIBITORS | Novartis AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007077186-A1 | PDF INHIBITORS | NOVARTIS AG (CH) | 2007-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318445-A1 | PDF INHIBITORS | PDF, TIMP3, MMP2 | HPGDS 476/4885L3MBTL1 3997/4885NPC1 1906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.