Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13674563 | 1.00 | BMPR1B (0.36) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL4507642 | 0.93 | EPHX2 (0.41) | EPHX2NR1H4GAAHPGDMAPK1 | |
| SCHEMBL4528144 | 0.87 | ACVRL1 (0.38) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL13674541 | 0.87 | ACVRL1 (0.38) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL4528168 | 0.87 | BMPR1B (0.38) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL13674531 | 0.87 | BMPR1B (0.38) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL5543796 | 0.84 | HSD11B1 (0.37) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL13674535 | 0.84 | HSD11B1 (0.37) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL13674533 | 0.84 | ACVRL1 (0.36) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL4518204 | 0.84 | ACVRL1 (0.38) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1864971-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2007-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | BMPR1B 3003/4885BMPR1A 2912/4885TGFBR1 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.