SCHEMBL45191

SCHEMBL45191

c1ccc(N2CN(c3cc(N4CN(c5ccccc5)c5ccccc54)cc(N4CN(c5ccccc5)c5ccccc54)c3)c3ccccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPT P10636 3/20 0.36
ATM Q13315 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 2/20 0.35
HPGD P15428 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12153468 0.93 SIGMAR1 (0.48) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL30261935 0.93 SIGMAR1 (0.48) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL24086865 0.86 MAPT (0.44) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL28148719 0.84 SIGMAR1 (0.41) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL2493726 0.80 SIGMAR1 (0.39) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL14339392 0.80 ALDH1A1 (0.46) MEN1KMT2AATMTDP1GAA
SCHEMBL12787331 0.79 SIGMAR1 (0.41) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL12514329 0.79 ALDH1A1 (0.42) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL3805314 0.77 SIGMAR1 (0.40) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL12153469 0.77 MAPT (0.42) SIGMAR1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10923688-B2 Quantum-dot light-emitting diode and method for producing quantum-dot light-emitting diode UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) 2021-02-16 US claimed
US-20200343489-A1 QUANTUM-DOT LIGHT-EMITTING DIODE AND METHOD FOR PRODUCING QUANTUM-DOT LIGHT-EMITTING DIODE UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) 2020-10-29 US claimed
US-8609258-B2 Light emitting devices and compositions NITTO DENKO CORPORATION (JP) 2013-12-17 US claimed
US-8597803-B2 Light emitting devices and compositions NITTO DENKO CORPORATION (JP) 2013-12-03 US claimed
US-20120305895-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2012-12-06 US claimed
US-20120273765-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2012-11-01 US claimed
US-20100231125-A1 ORGANIC LIGHT EMITTING DEVICE TO EMIT IN NEAR INFRARED NITTO DENKO CORPORATION (JP) 2010-09-16 US claimed
WO-2010104875-A1 ORGANIC LIGHT EMITTING DEVICE TO EMIT IN THE NEAR INFRARED NITTO DENKO CORPORATION (JP) 2010-09-16 WO claimed
US-20090179552-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-07-16 US claimed
WO-2009064661-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-05-22 WO claimed
US-20090066234-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-03-12 US claimed
WO-2009006550-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-01-08 WO claimed
WO-2008049577-A1 ORGANIC OPTO-ELECTRONIC DEVICES DSM IP ASSETS B.V. (NL) 2008-05-02 WO claimed
US-20240130150-A1 LIGHT EMITTING DEVICE AND METHOD OF MANUFACTURING THE SAME OREGON STATE UNIVERSITY (US) 2024-04-18 US disclosed
US-20240008358-A1 TRIPLET QUENCHING THE UNIVERSITY OF QUEENSLAND (AU) 2024-01-04 US disclosed
EP-3360175-B1 FORMULATIONS COMPRISING AT LEAST TWO ORGANIC SEMICONDUCTING COMPOUNDS AND AT LEAST TWO SOLVENTS MERCK PATENT GMBH (DE) 2023-05-17 EP disclosed
WO-2006097717-A1 HIGHLY BRANCHED DENDRIMERS ISIS INNOVATION LIMITED (GB) 2006-09-21 WO disclosed
EP-1636322-A1 ORGANIC PHOSPHORESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE ISIS INNOVATION LIMITED (GB) 2006-03-22 EP disclosed
US-20060040136-A1 Method of making an optical device CDT OXFORD LTD. (GB) 2006-02-23 US disclosed
WO-2004101707-A1 ORGANIC PHOSPHORESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE ISIS INNOVATION LIMITED (GB) 2004-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066234-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS MAP1LC3A, MAP1LC3C, CRY1 SIGMAR1 2998/4885NPC1 3835/4885RAB9A 962/4885
US-20120305895-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS ILK, CRY1, IK SIGMAR1 2788/4885NPC1 3013/4885RAB9A 512/4885
US-20090179552-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS CYBA, LIMA1, CRY1 SIGMAR1 2136/4885NPC1 3302/4885RAB9A 850/4885
US-20120273765-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS CYBA, LIMA1, CRY1 SIGMAR1 2136/4885NPC1 3302/4885RAB9A 850/4885
US-20240008358-A1 TRIPLET QUENCHING CCNT1, CCNA1, CCNA2 SIGMAR1 3084/4885NPC1 3683/4885RAB9A 3529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.