Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4530032 | 0.88 | ALDH1A1 (0.34) | L3MBTL3ALDH1A1MBTD1PKMKMT2A | |
| SCHEMBL4520212 | 0.84 | PTPN2 (0.47) | ALDH1A1CYP2C19KMT2A | |
| SCHEMBL4355595 | 0.83 | POLB (0.54) | ACHEALDH1A1CYP2C19 | |
| SCHEMBL4357579 | 0.82 | PTPN2 (0.44) | ACHEALDH1A1CYP2C19KMT2A | |
| SCHEMBL4529914 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1CYP2C19KMT2A | |
| SCHEMBL13586029 | 0.82 | PTPN2 (0.44) | ALDH1A1CYP2C19KMT2A | |
| SCHEMBL4537918 | 0.80 | PTPN2 (0.43) | ACHEALDH1A1CYP2C19 | |
| SCHEMBL13586060 | 0.80 | SMN1; SMN2 (0.47) | L3MBTL3ACHEALDH1A1CYP2C19KMT2A | |
| SCHEMBL4349922 | 0.80 | PTPN2 (0.43) | ACHEALDH1A1CYP2C19 | |
| SCHEMBL4538215 | 0.80 | PTPN2 (0.45) | ACHEALDH1A1CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |