Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4533655 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL4526460 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL4530032 | 0.82 | ALDH1A1 (0.34) | NPC1RAB9AKMT2AFAAHALDH1A1 | |
| SCHEMBL4520359 | 0.82 | L3MBTL3 (0.43) | CYP2C19KMT2AALDH1A1 | |
| SCHEMBL4355143 | 0.82 | GPR119 (0.46) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL4351624 | 0.82 | ENPP2 (0.44) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL4536272 | 0.81 | KMT2A (0.43) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL4352115 | 0.80 | GPR119 (0.46) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL4350085 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL4536182 | 0.80 | GPR119 (0.45) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |