Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPR3 | P17342 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13921823 | 0.93 | SYK (0.55) | SYKNFKB1BRD4METCYP17A1 | |
| SCHEMBL23345470 | 0.87 | POLB (0.60) | SYKNFKB1CYP17A1POLBNAMPT | |
| SCHEMBL13921831 | 0.86 | RAB9A (0.51) | SYKBRD4RAB9A | |
| SCHEMBL13921824 | 0.86 | SYK (0.60) | SYKBRD4METCYP17A1NAMPT | |
| SCHEMBL27714837 | 0.83 | NPC1 (0.58) | NFKB1POLBNAMPTNPC1RAB9A | |
| SCHEMBL4518592 | 0.82 | FCGR3B (0.53) | SYKBRD4METNPR3EGFR | |
| SCHEMBL29029431 | 0.82 | HDAC3 (0.56) | SYKBRD4CYP17A1NAMPTHDAC3 | |
| SCHEMBL3246720 | 0.81 | POLB (0.68) | NFKB1POLBRAB9ASRCHSD17B10 | |
| SCHEMBL29537493 | 0.81 | BRD4 (0.53) | SYKBRD4METCYP17A1NAMPT | |
| SCHEMBL28850302 | 0.81 | SYK (0.50) | SYKBRD4CYP17A1NAMPTCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090068169-A1 | 2,4,6-triamino-s-triazine-based compounds which bind to the tail (fc) portion of immunoglobulins and their use | PROMETIC BIOSCIENCES INC. (CA) | 2009-03-12 | — | — | US | disclosed |
| US-20090068169-A1 | 2,4,6-triamino-s-triazine-based compounds which bind to the tail (fc) portion of immunoglobulins and their use | PROMETIC BIOSCIENCES INC. (CA) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068169-A1 | 2,4,6-triamino-s-triazine-based compounds which bind to the tail (fc) portion of immunoglobulins and their use | FCGR2A, FCGR3B, FCGR1A | SYK 71/4885NFKB1 2115/4885BRD4 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.