Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KDM5C | P41229 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 7/20 | 0.38 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CTH | P32929 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3192012 | 0.89 | MCL1 (0.43) | LMNAPHF8KDM2AEGLN1KDM4E | |
| SCHEMBL14103450 | 0.83 | — | — | |
| SCHEMBL13525115 | 0.83 | CA1 (0.42) | LMNAPHF8KDM2AEGLN1KDM4E | |
| SCHEMBL4816014 | 0.80 | LMNA (0.50) | LMNAPHF8KDM2AEGLN1KDM4E | |
| SCHEMBL27023 | 0.80 | — | — | |
| Acetic Acid SCHEMBL30401693 | 0.77 | CTH (0.48) | LMNAPHF8KDM2AEGLN1KDM4E | |
| Acetic Acid SCHEMBL31437203 | 0.77 | CTH (0.48) | LMNAPHF8KDM2AEGLN1KDM4E | |
| SCHEMBL4015593 | 0.76 | LMNA (0.47) | LMNAPHF8KDM2AEGLN1KDM4E | |
| Water SCHEMBL11785760 | 0.76 | LMNA (0.47) | LMNAPHF8KDM2AEGLN1KDM4E | |
| SCHEMBL3464176 | 0.76 | LMNA (0.47) | LMNAPHF8KDM2AEGLN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372574-A1 | IN VIVO DETECTION OF SURGICAL MATERIALS | NORTHWESTERN UNIVERSITY | 2023-11-23 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-10786582-B2 | Gd(III)-dithiolane gold nanoparticle conjugates | NORTHWESTERN UNIVERSITY (US) | 2020-09-29 | — | — | US | disclosed |
| US-20190321492-A1 | Gd(III)-Dithiolane Gold Nanoparticle Conjugates | NORTHWESTERN UNIVERSITY | 2019-10-24 | — | — | US | disclosed |
| US-8574608-B2 | Bactericidal silver surfactant delivery into coating and polymer compositions | Eastern Michigan Universtity (US) | 2013-11-05 | — | — | US | disclosed |
| US-20130259916-A1 | BACTERICIDAL SILVER SURFACTANT DELIVERY INTO COATING AND POLYMER COMPOSITIONS | EASTERN MICHIGAN UNIVERSITY (US) | 2013-10-03 | — | — | US | disclosed |
| US-8314121-B2 | Imidazolone derivatives, preparation thereof as drugs, pharmaceutical compositions, and use thereof as protein kinase inhibitors, in particular CDC7 | SANOFI (FR) | 2012-11-20 | — | — | US | disclosed |
| US-20090253679-A1 | NEW IMIDAZOLONE DERIVATIVES, PREPARATION THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF AS PROTEIN KINASE INHIBITORS, IN PARTICULAR CDC7 | SANOFI-AVENTIS (FR) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10786582-B2 | Gd(III)-dithiolane gold nanoparticle conjugates | GOLGA3, LGALS3, DSTN | LMNA 3361/4885PHF8 3698/4885KDM2A 4456/4885 |
| US-20090253679-A1 | NEW IMIDAZOLONE DERIVATIVES, PREPARATION THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF AS PROTEIN KINASE INHIBITORS, IN PARTICULAR CDC7 | CDC7, CDK7, CDK17 | LMNA 2415/4885PHF8 1687/4885KDM2A 3307/4885 |
| US-20130259916-A1 | BACTERICIDAL SILVER SURFACTANT DELIVERY INTO COATING AND POLYMER COMPOSITIONS | CAPG, CLTB, DSTN | LMNA 4263/4885PHF8 3797/4885KDM2A 4327/4885 |
| US-20190321492-A1 | Gd(III)-Dithiolane Gold Nanoparticle Conjugates | GOLGA3, LGALS3, DSTN | LMNA 3361/4885PHF8 3698/4885KDM2A 4456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.