Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13158912 | 0.85 | ALDH1A1 (0.39) | MAPTPOLBALDH1A1ATMRAB9A | |
| SCHEMBL27794544 | 0.79 | POLB (0.49) | MAPTPOLBALDH1A1HTR1BTRPA1 | |
| SCHEMBL7296849 | 0.78 | CA12 (0.43) | MAPTPOLBALDH1A1RAB9ANPC1 | |
| SCHEMBL25571686 | 0.78 | NCEH1 (0.60) | MAPTPOLBRAB9ANPC1NCEH1 | |
| SCHEMBL28410249 | 0.77 | POLB (0.51) | MAPTPOLBALDH1A1HTR1BTRPA1 | |
| SCHEMBL9869695 | 0.74 | POLB (0.49) | MAPTPOLBALDH1A1HTR1BTRPA1 | |
| SCHEMBL7281303 | 0.74 | CA12 (0.47) | MAPTPOLBALDH1A1RAB9ANPC1 | |
| SCHEMBL24813703 | 0.73 | TP53 (0.48) | MAPTPOLBALDH1A1ATMRAB9A | |
| SCHEMBL3338632 | 0.73 | SLC6A2 (0.38) | MAPTPOLBALDH1A1TRPA1RAB9A | |
| SCHEMBL1803105 | 0.72 | POLB (0.59) | MAPTPOLBALDH1A1HTR1BTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090299074-A1 | BENZO[b]THIOPHEN DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJIN PHARMA LIMITED (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090299074-A1 | BENZO[b]THIOPHEN DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJIN PHARMA LIMITED (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090299074-A1 | BENZO[b]THIOPHEN DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJIN PHARMA LIMITED (JP) | 2009-12-03 | — | — | US | disclosed |
| EP-1947097-A1 | BENZOÝb¨THIOPHEN DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | Teijin Pharma Limited (JP) | 2008-07-23 | — | — | EP | disclosed |
| JP-2007145827-A | BENZO[B]THIOPHENE DERIVATIVE AND PRODUCTION METHOD THEREOF | TEIJIN PHARMA LTD | 2007-06-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299074-A1 | BENZO[b]THIOPHEN DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | CMA1, TPSB2, CTRB1 | MAPT 2088/4885POLB 1436/4885ALDH1A1 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.