Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13158912 | 0.80 | ALDH1A1 (0.39) | TSHRMAPTGAALMNAALDH1A1 | |
| SCHEMBL22829872 | 0.78 | FABP7 (0.37) | TSHRMAPTLMNAALDH1A1HPGD | |
| SCHEMBL11631914 | 0.78 | NCEH1 (0.44) | MAPTGAALMNAALDH1A1HPGD | |
| SCHEMBL10737045 | 0.78 | THRB (0.52) | TP53CA2CA1MAPTGAA | |
| SCHEMBL4735587 | 0.76 | L3MBTL1 (0.41) | CA2CA1TSHRLMNAALDH1A1 | |
| SCHEMBL4730798 | 0.76 | TDP1 (0.47) | CA2TSHRMAPTGAAALDH1A1 | |
| SCHEMBL3763474 | 0.76 | ALDH1A1 (0.48) | TSHRGAALMNAALDH1A1HPGD | |
| SCHEMBL7266421 | 0.76 | L3MBTL1 (0.44) | TSHRMAPTGAAALDH1A1HPGD | |
| SCHEMBL8537943 | 0.76 | HTR7 (0.47) | TP53MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL10741372 | 0.76 | CA12 (0.59) | TP53CA2CA1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411417-A1 | HERBICIDAL THIAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411417-A1 | HERBICIDAL THIAZOLE COMPOUNDS | DDT, NQO2, SQOR | TP53 2927/4885CA2 182/4885CA1 1358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.