SCHEMBL45291

SCHEMBL45291

CC(Cl)Cc1cc(CC(C)Cl)cc(CC(C)Cl)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.33
SLC6A2 P23975 2/20 0.32
SLC6A3 Q01959 2/20 0.32
ALOX15 P16050 4/20 0.31
ALOX12 P18054 4/20 0.31
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 2/20 0.31
ALDH1A1 P00352 2/20 0.31
ESR1 P03372 2/20 0.31
TP53 P04637 2/20 0.31
CYP3A4 P08684 2/20 0.31
HPGD P15428 2/20 0.31
MAPK1 P28482 2/20 0.31
RECQL P46063 2/20 0.31
KMT2A Q03164 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 2/20 0.31
NR1I2 O75469 1/20 0.31
GMNN O75496 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45023 0.84 PNMT (0.52) PNMTSLC6A2SLC6A3LMNACYP2D6
SCHEMBL45261 0.83 HMGCR (0.46) TP53POLBHTR2ACYP2C19HTR2B
SCHEMBL45200 0.81 SLC6A2 (0.48) SLC6A2SLC6A3ESR1
SCHEMBL7764667 0.78 HMGCR (0.50) KDM4ETP53POLBHTR2ACYP2C19
SCHEMBL2332071 0.77 HTR2A (0.46) ALDH1A1TP53CYP3A4LMNACYP1A2
SCHEMBL66064 0.75 SIGMAR1 (0.58) SLC6A2SLC6A3MEN1KMT2ACYP2D6
SCHEMBL27878590 0.75 SIGMAR1 (0.58) SLC6A2SLC6A3MEN1KMT2ACYP2D6
Ammonia Solution, Strong SCHEMBL8142874 0.73 SIGMAR1 (0.56) SLC6A2SLC6A3MEN1KMT2ACYP2D6
Hydrochloric Acid SCHEMBL22207848 0.73 SIGMAR1 (0.56) SLC6A2SLC6A3MEN1KMT2ACYP2D6
SCHEMBL2326795 0.73 SLC6A2 (0.64) SLC6A2SLC6A3LMNAHTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795247-B2 Polyolefin dispersants and methods of making and using thereof THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-24 US claimed
US-20210189030-A1 Polyolefin Dispersants and Methods of Making and Using Thereof UNIVERSITY OF SOUTHERN MISSISSIPPI 2021-06-24 US claimed
US-20190284314-A1 Polyolefin Dispersants and Methods of Making and Using Thereof CHEVRON ORONITE COMPANY LLC. 2019-09-19 US claimed
EP-2387592-B1 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES THE UNIV OF SOUTHERN MISSISSIPPI (US) 2018-08-29 EP claimed
US-9650449-B2 Functionalization of polyolefins with phenoxy derivatives THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2017-05-16 US claimed
EP-2459599-B1 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS UNIV SOUTHERN MISSISSIPPI (US) 2016-07-20 EP claimed
US-20130131280-A1 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-05-23 US claimed
US-8394898-B2 In situ formation of hydroxy chain end functional polyolefins THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-03-12 US claimed
EP-2387592-A2 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES The University of Southern Mississippi (US) 2011-11-23 EP claimed
US-8063154-B2 Preparation of exo-olefin terminated polyolefins via quenching with alkoxysilanes or ethers THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-11-22 US claimed
US-6444768-B1 CONTINUOUS SLURRYING POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. 2002-09-03 US claimed
WO-2002050129-A1 PROCESS FOR POLYMERIZING CATIONICALLY POLYMERIZABLE MONOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-06-27 WO claimed
WO-2001036498-A1 PRODUCTION OF ISOBUTYLENE COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO claimed
EP-0609737-B1 Process for producing a halogenated butyl rubber BAYER INC (CA) 2000-06-07 EP claimed
EP-0609737-A2 Process for producing a halogenated butyl rubber BAYER RUBBER INC. (CA) 1994-08-10 EP claimed
US-RE34640-E Polymerizing isobutylene, adding monomer to make block polymer; metal halide, initiator and electron pair doner solvent UNIVERSITY OF AKRON (US) 1994-06-14 US claimed
EP-0341012-B1 UNIFORM MOLECULAR WEIGHT POLYMERS EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1992-12-30 EP claimed
WO-1991011468-A1 NEW THERMOPLASTIC ELASTOMERS THE UNIVERSITY OF AKRON (US) 1991-08-08 WO claimed
US-4946899-A CARBOCATIONIC POLYMERIZATION INVOLVING HOMOPOLYMERIZATION OF ELASTOMER FOLLOWED BY COPOLYMERIZATION TO ADD GLASSY SEGMENTS; FORMING LIVING POLYMERS WITH A METAL HALIDE, PROMOTER AND SOLVENT MIXTURE THE UNIVERSITY OF AKRON (US) 1990-08-07 US claimed
EP-0341012-A2 Uniform molecular weight polymers EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1989-11-08 EP claimed