Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 10/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 6/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720507 | 0.84 | ALOX5 (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4527458 | 0.82 | KDM4E (0.36) | CYP3A4CYP2C9NPC1RAB9ACYP1A2 | |
| SCHEMBL16720191 | 0.77 | KDM4E (0.38) | GAAKDM4E | |
| SCHEMBL16720555 | 0.77 | LMNA (0.40) | CYP3A4CYP2C9RAB9AGAACYP2C19 | |
| SCHEMBL28073818 | 0.75 | CYP2A6 (0.46) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 | |
| SCHEMBL16720689 | 0.71 | DYRK1A (0.45) | ALK | |
| SCHEMBL2091081 | 0.70 | NPC1 (0.42) | NPC1RAB9AGAAALDH1A1KDM4E | |
| SCHEMBL21295624 | 0.70 | CYP2A6 (0.45) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 | |
| SCHEMBL21296038 | 0.69 | NPC1 (0.41) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 | |
| SCHEMBL16720456 | 0.69 | BRD4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298865-A1 | Derivatives of pyrrolopyridine-2-carboxamides, preparation thereof and therapeutic application thereof | SANOFI-AVENTIS (FR) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298865-A1 | Derivatives of pyrrolopyridine-2-carboxamides, preparation thereof and therapeutic application thereof | PYCR1, ATP5PD, NQO2 | CYP2A6 981/4885CYP3A4 745/4885CYP2C9 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.