Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4529584 | 0.92 | NPC1 (0.50) | HSD11B1FLT1FLT4KDRMMP1 | |
| SCHEMBL7360995 | 0.82 | NPC1 (0.53) | HSD11B1MMP1MMP2MMP3MMP9 | |
| SCHEMBL4505612 | 0.81 | FLT1 (0.54) | HSD11B1FLT1FLT4KDRALDH1A1 | |
| SCHEMBL4520935 | 0.80 | KMT2A (0.50) | L3MBTL1ALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL12642017 | 0.76 | ALDH1A1 (0.50) | HSD11B1NPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL6201887 | 0.76 | HSD11B1 (0.87) | HSD11B1FLT1FLT4KDRL3MBTL1 | |
| SCHEMBL17965927 | 0.76 | RECQL (0.50) | HSD11B1MMP1MMP2MMP3MMP9 | |
| SCHEMBL7365162 | 0.74 | MMP2 (0.51) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL907263 | 0.74 | CA12 (0.55) | HSD11B1ALDH1A1KMT2AMAPTRECQL | |
| SCHEMBL17965928 | 0.74 | LMNA (0.50) | HSD11B1L3MBTL1MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090305264-A1 | COOPERATIVE PROBES AND METHODS OF USING THEM | FLUIDIGM CORPORATION | 2009-12-10 | — | — | US | disclosed |
| EP-1893741-A1 | CELL-BASED MICROARRAYS, AND METHODS FOR THEIR PREPARATION AND USE | Beckman Coulter, Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007001817-A1 | CELL-BASED MICROARRAYS, AND METHODS FOR THEIR PREPARATION AND USE | BECKMAN COULTER, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060292559-A1 | Cell-based microarrays, and methods for their preparation and use | BECKMAN COULTER, INC. (US) | 2006-12-28 | — | — | US | disclosed |
| US-5648213-A | IMMUNOASSAY | BECKMAN INSTRUMENTS, INC. (US) | 1997-07-15 | — | — | US | disclosed |