Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257647 | 0.84 | PTGS2 (0.38) | EPHX1ALDH1A1KMT2ANPSR1L3MBTL1 | |
| SCHEMBL8108217 | 0.84 | PTGS2 (0.38) | EPHX1ALDH1A1KMT2ANPSR1L3MBTL1 | |
| SCHEMBL8993499 | 0.84 | PTGS2 (0.38) | EPHX1ALDH1A1KMT2ANPSR1L3MBTL1 | |
| SCHEMBL14968177 | 0.77 | CYP3A4 (0.51) | ALDH1A1KMT2ANPSR1MAPTATM | |
| SCHEMBL14968090 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KMT2ANPSR1L3MBTL1PTGS2 | |
| SCHEMBL8746743 | 0.74 | ALDH1A1 (0.34) | ALDH1A1KMT2AL3MBTL1LMNAF2 | |
| SCHEMBL11245264 | 0.74 | KMT2A (0.43) | EPHX1ALDH1A1KMT2ANPSR1L3MBTL1 | |
| SCHEMBL10338619 | 0.74 | EPHX1 (0.41) | EPHX1ALDH1A1KMT2ANPSR1L3MBTL1 | |
| SCHEMBL14968092 | 0.73 | CYP3A4 (0.38) | ALDH1A1KMT2ANPSR1L3MBTL1LMNA | |
| SCHEMBL14967286 | 0.73 | RORC (0.39) | KMT2ANPSR1L3MBTL1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040319-A1 | METHODS OF IMPROVING CANCER CHEMOTHERAPY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-02-28 | — | — | WO | disclosed |
| WO-2017120012-A1 | METHODS OF TREATING MENTAL DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-07-13 | — | — | WO | disclosed |
| WO-2009105723-A2 | NOVEL METHODS FOR BONE TREATMENT BY MODULATING AN ARACHIDONIC ACID METABOLIC OR SIGNALING PATHWAY | ACCELALOX, INC. (US) | 2009-08-27 | — | — | WO | disclosed |
| WO-2000023060-A2 | METHOD OF TREATING IMMUNOLOGICAL DISORDERS MEDIATED BY T-LYMPHOCYTES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-04-27 | — | — | WO | disclosed |