Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 5/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2842642 | 0.82 | OPRL1 (0.70) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL8112806 | 0.81 | OPRM1 (0.51) | OPRM1OPRL1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL2846505 | 0.75 | GAA (0.68) | ALDH1A1KMT2A | |
| SCHEMBL2636899 | 0.75 | CA12 (0.66) | ADRA1DADRA1AADRA1BOPRM1OPRL1 | |
| SCHEMBL4533417 | 0.73 | ALDH1A1 (0.66) | OPRM1OPRL1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL14031243 | 0.73 | CA12 (0.62) | ADRA1DADRA1AADRA1BOPRM1OPRD1 | |
| SCHEMBL2843906 | 0.73 | ALDH1A1 (0.65) | ALDH1A1 | |
| SCHEMBL7696075 | 0.72 | CYP2D6 (0.62) | OPRM1OPRL1OPRD1CA12CA1 | |
| SCHEMBL2841585 | 0.72 | NPY2R (0.51) | ALDH1A1KMT2A | |
| SCHEMBL8714542 | 0.70 | CA12 (0.62) | ADRA1DADRA1AADRA1BOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC11, HDAC3 | ADRA1D 2777/4885ADRA1A 2560/4885ADRA1B 2617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.