Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891352 | 0.92 | PKM (0.56) | ALDH1A1HSD17B10CYP1A2SMYD3RAB9A | |
| SCHEMBL12277779 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HSD17B10CYP1A2SMYD3RAB9A | |
| Hydrochloric Acid SCHEMBL2417809 | 0.88 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP1A2SMYD3RAB9A | |
| SCHEMBL2851310 | 0.84 | GPR35 (0.48) | CYP1A2RAB9APOLBCSNK2A1MAPT | |
| SCHEMBL21460235 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HSD17B10CYP1A2SMYD3RAB9A | |
| SCHEMBL1901172 | 0.83 | ALDH1A1 (0.76) | ALDH1A1HSD17B10CYP1A2RAB9APOLB | |
| SCHEMBL4218472 | 0.80 | DCUN1D1 (0.62) | ALDH1A1RAB9APOLBMAPTKMT2A | |
| SCHEMBL2418491 | 0.79 | ALDH1A1 (0.61) | ALDH1A1RAB9AL3MBTL1MAPT | |
| SCHEMBL4714652 | 0.76 | HSD17B10 (0.71) | ALDH1A1HSD17B10CYP1A2RAB9APOLB | |
| SCHEMBL1487964 | 0.76 | ALDH1A1 (0.66) | ALDH1A1HSD17B10CYP1A2RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | PLE PATRICK | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | AQP3, AQP1, F12 | ALDH1A1 2449/4885HSD17B10 4746/4885CYP1A2 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.