Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | KDM5A | P29375 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4539162 | 0.82 | KMT2A (0.43) | HCAR2HCAR3 | |
| SCHEMBL4530922 | 0.81 | HCAR2 (0.44) | HCAR2HCAR3KDM5A | |
| SCHEMBL4533064 | 0.74 | — | — | |
| SCHEMBL19924463 | 0.73 | HCAR3 (0.70) | HCAR2HCAR3KDM5A | |
| SCHEMBL23844535 | 0.72 | HCAR2 (0.53) | HCAR2HCAR3KDM5A | |
| SCHEMBL29520017 | 0.72 | HCAR2 (0.53) | HCAR2HCAR3KDM5A | |
| SCHEMBL29520019 | 0.72 | HCAR2 (0.53) | HCAR2HCAR3KDM5A | |
| SCHEMBL15484324 | 0.70 | ALOX15 (0.48) | HCAR2HCAR3KDM5A | |
| SCHEMBL11220340 | 0.66 | SMN1; SMN2 (0.43) | HCAR2 | |
| SCHEMBL30996674 | 0.64 | TSHR (0.42) | HCAR2HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090075980-A1 | Pyrazolopyridines and Analogs Thereof | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075980-A1 | Pyrazolopyridines and Analogs Thereof | IL4, IL4I1, IL2 | HCAR2 827/4885HCAR3 1497/4885KDM5A 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.