Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272398 | 0.79 | PCSK9 (0.39) | HTTTSHRNAAAALDH1A1 | |
| SCHEMBL28743025 | 0.76 | NAAA (0.43) | HTTNAAAALDH1A1 | |
| SCHEMBL272865 | 0.74 | ESR1 (0.37) | CYP2C19MEN1KMT2ACYP1A2NAAA | |
| SCHEMBL16347775 | 0.73 | HTT (0.36) | HTTCYP2C19MEN1GLAKMT2A | |
| SCHEMBL4522874 | 0.73 | TAAR1 (0.43) | MEN1KMT2ASIGMAR1HRH3ALDH1A1 | |
| SCHEMBL6841739 | 0.71 | ALDH1A1 (0.32) | GLAALDH1A1 | |
| SCHEMBL4533823 | 0.71 | MAOA (0.40) | MAOASMN1; SMN2 | |
| SCHEMBL3353015 | 0.70 | HTT (0.42) | HTTCYP2C19MEN1GLAKMT2A | |
| SCHEMBL4512319 | 0.69 | CYP2C19 (0.52) | CYP2C19MEN1GLAKMT2AHRH4 | |
| SCHEMBL272887 | 0.69 | ESR1 (0.39) | GLATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507480-B2 | Corrosion-resistant metal surfaces | BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) | 2009-03-24 | — | — | US | disclosed |
| US-20060269760-A1 | Corrosion-resistant metal surfaces | ENERGY, UNITED STATES DEPARTMENT OF | 2006-11-30 | — | — | US | disclosed |